The most important fact justifying aging/longevity drug discovery is that *lifespan-extending drugs exist.* Lots of them. If you screen 1280 well-known drugs and natural products on nematode worms, 5% of them significantly extend lifespan. https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.12163 …
-
Show this thread
-
Replying to @s_r_constantin
Just curious: how much have we progressed in simulating organisms for testing drugs? Is it possible to perhaps to filter out the least promising drugs by means of a simulation? Is any work even being done in this direction
1 reply 0 retweets 0 likes
Replying to @OneBigOh
we're really not there yet. protein binding simulations are ok but not yet a substitute for experiment; organism simulations are totally not ready.
8:36 AM - 20 May 2019
0 replies
0 retweets
1 like
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.