The most important fact justifying aging/longevity drug discovery is that *lifespan-extending drugs exist.* Lots of them. If you screen 1280 well-known drugs and natural products on nematode worms, 5% of them significantly extend lifespan. https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.12163 …
-
-
That's what we're doing at Daphnia Labs: big phenotypic screens on the small crustacean Daphnia magna. (Currently we're at the prototype stage.)
Show this thread -
In principle, gene therapies can be much more flexible and powerful tools than small molecules, and I'm impressed by some of the results so far (e.g. Oisin's DNA-targeting senolytics.) But small molecules can be tested faster, and some of them are already FDA-approved.
Show this thread
End of conversation
New conversation -
-
-
I think you will really appreciate my PhD project. ;) I started DrugAge as part of my Masters, and I had this exact same thought. I hope to come through in a few months (with some added bonuses besides large-scale automation and machine learning).
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.