https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834185/ … Video phenotypic screens for neuroactive drugs in zebrafish; in broad strokes, zebrafish behavior responds to drugs in "predictable" directions. Stimulants speed up motion, anxiolytics slow it down.
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Bottom line is that this is evidence video-based, behavioral phenotypic screening adds value. Recapitulates stuff we know from independent sources (similar chemical structures) and adds stuff we don't (bioactivity).
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