Consumer biomarker-testing kits (like 23andme, and the equivalents for whole-genome sequencing, proteomics, microbiome, etc) don't make a ton of practical sense to me as a path towards new medical treatments.
Meanwhile, large (>100,000) biobanks funded by universities, governments, and nonprofits, may be an equally good resource for research discovering new correlations between biomarkers and diseases. Some countries collect data & samples from all their citizens!
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To what degree so you see such data collection affecting privacy? As a lay person, if like to know if Gattaca to situations are possible.
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It is absolutely possible to uniquely identify someone by their genome (or even an array of SNPs, maybe.) And risk prediction scores for polygenic traits (such as heart disease or schizophrenia) are getting better. Yes, Gattaca is technically possible.
End of conversation
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There are a lot of GWAS and similar studies coming out of countries with good national health systems. Based on their results, it doesn’t look like we’re far away from being able to do good PGS on WGS/WES...
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