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Rob Menzies proslijedio/la je TweetHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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Rob Menzies proslijedio/la je Tweet
If you didn't think the biology of and potential for exosomes for diagnosis and therapies was awesome, this review
@sciencemagazine will change your mind https://science.sciencemag.org/content/367/6478/eaau6977 … by@KalluriLab and Valerie LeBleu@MDAndersonNews w/@ScienceVisualspic.twitter.com/JS0zLXlWFE
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Rob Menzies proslijedio/la je Tweet
Tremendously excited about our
@NEJM publication today that brings together clinical, in-vivo and in-vitro studies tackling the challenge of#AKI through identifying#suPAR as a potential therapeutic target. Read on (tweetorial)!https://www.nejm.org/doi/full/10.1056/NEJMoa1911481 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Rob Menzies proslijedio/la je Tweet
A prime example of a great explainer for a complex topic: my brilliant friend
@UrnovFyodor, aka Gene Editor, explains#CRISPR genome editing and search-and-replace (prime) editing https://www.nejm.org/doi/full/10.1056/NEJMcibr1914271 … re: https://www.nature.com/articles/s41586-019-1711-4 …@nature@davidrliupic.twitter.com/1lmWsdEVYi
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Rob Menzies proslijedio/la je Tweet
Important paper out on
#Wuhan#nCoV2019 via@biorxivpreprint 96% sequence identity to a bat#coronavirus ~80% sequence identity to SARS ~95% AA sequence identity in 7 conserved replicase domains to SARS uses the same cell entry receptor, ACE2, as SARS https://www.biorxiv.org/content/10.1101/2020.01.22.914952v1.full.pdf …pic.twitter.com/dGEjBvGx4j
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Rob Menzies proslijedio/la je Tweet
If more scientists calculated confidence distributions, they would realise that a point estimate is a value in which you have zero confidence.pic.twitter.com/8oUo3EzOUt
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Enjoying this from
@SafiBahcall on @business. Speaks to my own experience moving from physics and academia into biology and biopharma. Scientific rigor and serendipity are key ingredients in drug discoveryhttps://podcasts.apple.com/gb/podcast/masters-in-business/id730188152?i=1000462914351 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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Rob Menzies proslijedio/la je Tweet
A study of a Finnish sibling pairs with type 1 diabetes aimed at identifying DNA patterns associated with diabetic nephropathy found that the genes encoding two protein kinase C isoforms were the most strongly associated with the condition. http://bit.ly/2R4GBhM pic.twitter.com/UWp9nQlWot
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Rob Menzies proslijedio/la je Tweet
Observational studies have long suggested that patients with diabetes have an elevated risk of developing Alzheimer disease and other forms of dementia, and a growing body of evidence suggests that glucose hypometabolism may be a key player in dementia p… https://ja.ma/2t4e18l pic.twitter.com/UGKaHtt9Eo
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Rob Menzies proslijedio/la je Tweet
Our review of recent past & near future of human disease genetics (1990-2030) has just been published in Nature (https://www.nature.com/articles/s41586-019-1879-7 …). Thanks to co-authors too numerous to list, & to
@obahcall et al at Nature (including the reviewers) for pulling this together.#humgen25 1/nPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Rob Menzies proslijedio/la je Tweet
New and emerging modalities continued to accumulate FDA approvals in 2019, including a first approval for a nanobody and several approved antibody–drug conjugates - find out more here https://go.nature.com/2s9AHnm pic.twitter.com/QlDVIj1LXY
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Rob Menzies proslijedio/la je Tweet
The Piezo ion channels story—how cells sense touch and pressure—is playing out to be much bigger than initially envisioned (including pain and beyond neurons) https://www.nature.com/articles/d41586-019-03955-w …
@NatureNews by@amberldance w/@ardemp@scrippsresearch#openaccesspic.twitter.com/GofqmDCr5l
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Rob Menzies proslijedio/la je Tweet
Helpful discussion on the importance of permeability in targeted protein degradation, based on recent work out of UNC.
@Dereklowe blog in@ScienceTM:Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Rob Menzies proslijedio/la je Tweet
How the periodic table was created is a perfect illustration of how science progresses, as we explored on its birthdayhttps://econ.st/2rB1N6C
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Rob Menzies proslijedio/la je Tweet
2019 will be remembered for the 1st hyper-personalized, true N of 1, from sequence to therapy in < 1 year https://www.nature.com/articles/s41591-019-0700-3.pdf …
@NatureMedicine https://worldin.economist.com/article/17520/edition2020creating-personalised-drugs?navigation=true&category=extra …@TheEconomist@natashaloder https://www.nejm.org/doi/pdf/10.1056/NEJMoa1813279?articleTools=true …@NEJM@timyu@BostonChildrens https://www.statnews.com/2018/10/22/a-tailor-made-therapy-may-have-halted-a-rare-disease/ …pic.twitter.com/wTNq22LQfH
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Rob Menzies proslijedio/la je Tweet
A
@NatureBiotech paper shows the largest reference phosphoproteome of almost 120,000 human phosphosites. To identify those likely to be critical, researchers used a machine learning approach capable of ranking them according to functional importance. https://go.nature.com/2YFT8Mn pic.twitter.com/jXAqQPZMaE
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Rob Menzies proslijedio/la je Tweet
Check out our **just published** review in
@NatRevNeph We (@ClatworthyLab) review how#singlecell allows us to probe immunity, and the implications this has for#nephrology https://www.nature.com/articles/s41581-019-0227-3 …


pic.twitter.com/Y2Uy8TeZqj
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Rob Menzies proslijedio/la je Tweet
How many genes are there in the human genome? In 2018 the consensus was ~21,000 https://www.nature.com/articles/d41586-018-05462-w … Now
@salkinstitute investigators say "we expanded the genome" by >2,000 small genes (smORFs) https://www.nature.com/articles/s41589-019-0425-0 …@nchembio https://www.salk.edu/news-release/finding-the-smallest-genes-could-yield-outsized-benefits/ …@alansaghatelianpic.twitter.com/ajsAdRj2nP
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Rob Menzies proslijedio/la je Tweet
Platelet activation at the site of vascular injury from our 2018 review on platelets in
#AKI by Joris Roelofs & colleagues https://go.nature.com/2Lnc7UO pic.twitter.com/2XyfmkQT8t
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