Natural experiments have informed neuroscience for centuries. An intriguing case is that of humans without a cerebellum (cerebellar agenesis). Check also recent work showing one side of the brain helps correct the activity of the other https://www.nature.com/articles/nature22324 … .
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Agree. For me the big puzzle is this: since there's a repeatable pattern of brain development leading to a well-defined (and lateralised) arrangement of areas, how can a complete disruption be compensated by an asymmetric, new arrangement?
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Information, and more importantly function, has to be highly distributed and dynamic. There must be some intriguing theory to explore around designing our own such systems.
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Indeed. It is rather puzzling that, given that some given areas (such language's-related ones in the left side) can just reorganise in the right one after hemispherectomy. We do need to explain this.
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Amazing indeed; check this out: : "Is your brain really necessary" - some rare people have pretty normal cognition and behavior despite radically small brains: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=6909910 … (there are a few other papers on this)
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Thanks for the ref! To me the most amazing thing is that brain areas that are required to deal with given functions become fully reorganised at the other side of the brain. Language f.ex. goes to the right side if the left has been removed.
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The crazy thing is: sometimes brain can adjust for half of the cortex missing, yet sometimes everything goes haywire due to a tiny change in one protein;https://twitter.com/ThePostsynaptic/status/910761920591929344 …
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But we are talking about very different levels/Scales. A whole, already developed brain become deeply challenged with a loss of half its architecture and yet, it re-arranges itself in a completely new way. Too much for me.
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