Rick Huganir

@rhuganir

I am a neuroscientist at Johns hopkins University interested in the molecular mechanisms underlying learning and memory in health and disease.

Baltimore, MD, USA
Vrijeme pridruživanja: veljača 2010.

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  1. proslijedio/la je Tweet
    1. velj

    Check out this new review published by the on NMDA trafficking by Vieira and collaborators. Regulation of NMDA glutamate receptor functions by the GluN2 subunits

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  2. proslijedio/la je Tweet
    2. velj

    New lab preprint! Very interesting data showing how different splice isoforms of SynGAP1 orchestrate different aspects of neurodevelopment and synaptic plasticity.

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  3. proslijedio/la je Tweet
    31. sij

    FYI ... more great work from the lab about and it’s isforms. So much to learn about this important gene!

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  4. proslijedio/la je Tweet

    Another great paper from lab helping us to understand the isoforms of . Important part: the bit where our support for this lab gets a mention... we are so glad to be able to support a better understanding of this important gene. BTW: 501 patients and counting.

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  5. 30. sij

    My lab's first preprint on bioRxiv demonstrating how SynGAP1 splice variants and liquid-liquid phase transtions regulate dendritic developement and synaptic plasticity. Has intesrresting basic biology findings and relevance to SynGAP1 related disorders.

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  6. proslijedio/la je Tweet
    28. sij

    Pinching myself... our venue for the group dinner tonight. Well done 🙆🏼‍♀️

    , , i još njih 7
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  7. 26. sij

    My brilliant wife speaking at 2019 Conscious Cities Festival

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  8. proslijedio/la je Tweet
    26. sij
    Odgovor korisniku/ci

    Lots new. Because of the size and methods, now have a gene list for “causal” loci and they can be put into two groups, ASD +/- cog impairment. For those of us that model “what they do”, now have a roadmap for which ones to study and in what context. Been waiting for this.

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  9. 26. sij

    We need to know what genes are involved before we figure out what they do to have impact on the disease. Much of this paper is new. Large exome sequencing studies are needed to identify the genes with the largest impact on the disorder.

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  10. proslijedio/la je Tweet
    25. sij

    There are some good people. Schiff is one of them. Makes me cry and gives me hope for our country.

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  11. proslijedio/la je Tweet
    24. sij
    Odgovor korisniku/ci

    That's garbage. That PI is mistaken. Hours worked has no correlation with scientific productivity. Some of my best scientists worked 9am-5pm, had hobbies, families.

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  12. proslijedio/la je Tweet
    25. sij

    Dear Mary Louise Kelly, you are a bulwark of democracy. Thank you and please keep at it. Sincerely, the American People

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  13. proslijedio/la je Tweet

    Check out the new issue of for a compelling Q&A interview with PIN faculty member and overall star Dr. Tom Blanpied ()!

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  14. proslijedio/la je Tweet
    22. sij

    Rockefeller's Leslie Vosshall () has been named the 2020 recipient of Pradel Research Award! She is honored for her research into how disease-carrying mosquitoes select human hosts. Congratulations!

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  15. proslijedio/la je Tweet
    21. sij

    . flies back to Belgium this weekend to be inducted into country's Royal Academy of Medicine. Our lucky team gets to hear his practice talk on Thursday. Got a preview of his slides this morning and they are 🙌

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  16. proslijedio/la je Tweet
    20. sij

    Happy to share our recent preprint on how SynGAP splicing enables plasticity thresholds at excitatory synapses. Implications for L&M, as well as disease, including an approach to treat SYNGAP1-related neurodevelopmental disorders.

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  17. 8. sij
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  18. proslijedio/la je Tweet
    8. sij

    It's not just my friend, it's thousands of other small businesses, wine bars, wholesalers, servers whose livelihood will disappear overnight The Insanity of Trump’s Wine Tariffs 2/n

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  19. proslijedio/la je Tweet
    3. sij

    This work was done in three different labs (, Mark Bear and ours) using multiple Arc KO lines and using various LTP induction protocols. We found NO LTP deficits in ANY mouse line or induction protocol. In fact, theta burst CA1 LTP was enhanced in germline KOs.../4

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  20. proslijedio/la je Tweet
    3. sij

    First preprint of the decade! Congrats to for pushing this through some tough times. We are interested in how neurons store information at the molecular level. We think the plasticity gene Arc is a key player in memory consolidation.... /1

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