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How hard would you work to prevent loss of $5? As hard as you’d be willing to work to gain $5? Most tend to work harder to prevent loss. This excellent work by @GaleaLab @xiulichen618 explores this question and links loss aversion to dopamine.https://www.jneurosci.org/content/40/3/661 …
They measured the willingness to produce force to attain reward or prevent loss. Healthy people tend to produce more force to prevent loss. This is also true in Parkinson's disease. But in PD, the patients show smaller loss aversion than normal.pic.twitter.com/edrmBUlpvf
Dopamine depletion tends to make animals less willing to exert effort for reward, though the willingness to prevent loss is less understood. Here, in medicated PD, the results show a reduced willingness to exert effort in order to prevent loss.
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