Peter Nollert

@reducentropy

How do membrane proteins work? Enjoying protein structure/function stories, drug discovery and cutting edge bio-technologies.

Seattle, WA
Vrijeme pridruživanja: veljača 2009.

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  1. Prikvačeni tweet
    8. velj 2018.

    Everything about lipids that you'd ever want to know. In-depth review

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  2. 3. velj

    Read my Feb 3 'Membrane Proteins/SBDD' Newsletter featuring Channel mechanics

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  3. 1. velj
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  4. 31. sij

    delivers again: how B get activated E.g. CRF1 receptor

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  5. 31. sij

    Need dynamics to understand malaria transporter glucose/fructose promiscuity Structure info only is insufficient

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  6. 31. sij

    Amazing (?): Cholesterol is an endogenous allosteric modulator of CB1

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  7. 30. sij

    Promising new fine-tunable oligoglycerol detergents for membrane protein & purification / structures ?

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  8. proslijedio/la je Tweet
    27. sij

    Latest paper now online But no K+ this time! Just beautiful big holes... (Calcium homeostasis modulators, CALHMs). Very grateful to Hiro Furukawa and to be able to collaborate on this one...

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  9. proslijedio/la je Tweet
    27. sij

    Structure of the Bcs1 AAA-ATPase suggests an airlock-like translocation mechanism for folded proteins

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  10. 27. sij

    Read my Jan 27 'Membrane Proteins/SBDD' Newsletter featuring Layers & channels

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  11. 24. sij

    How to properly engineer helix-helix fusions to help transmembrane protein crystallization

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  12. 21. sij

    mg production for X-ray crystallographic structure determination State-of-the-art gene design, expression & purification strategies, protein thermostabilisation methods

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  13. 20. sij

    Read my Jan 20 'Membrane Proteins/SBDD' Newsletter featuring Trove of complexes

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  14. 10. sij

    Peptides not necessary to modulate class B Unexpected molecular mechanism of action for drug orally active-like compound bound to glucagon-like peptide-1 (GLP-1)

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  15. 31. pro 2019.

    Last structure of the year (?) Angiotensin bound to Angiotensin receptor ?

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  16. proslijedio/la je Tweet
    30. pro 2019.

    Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein.

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  17. proslijedio/la je Tweet
    29. pro 2019.

    Congratulations to Ping and Chuangye! Cryo-EM Structure of the Human Mitochondrial Translocase TIM22 Complex

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  18. proslijedio/la je Tweet

    Congratulations to Toshi's and Hiro's teams!!!

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  19. proslijedio/la je Tweet

    Structural basis for pore blockade of the human cardiac sodium channel Nav1.5 by tetrodotoxin and quinidine

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  20. proslijedio/la je Tweet

    Crystal structure of a human plasma membrane phospholipid flippase

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  21. proslijedio/la je Tweet
    26. pro 2019.

    Crystal structure of heliorhodopsin 48C12 Figure1つの速報形式。TaHeRとのRMSDは0.693 Å。Sf9で発現させていたのは意外だった。あと、チャネル活性を調べるにあたり、PCにChRmineを使ってくれていたことに少し驚いた。

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