Even if CRISPR only ever works on algae, yeast, etc it'll be hugely transformative. This alone will effectively provide the ability to create wet nanotech strains customized for the creation of industrial adhesives, solvents, pharmaceuticals, etc.https://twitter.com/statnews/status/1018873225206525952 …
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I've been going off the "oh, of course evolution would bake layered defenses against genetic modification by external viruses into our cells, this is probably not going to be easy" ever since someone pointed it out to me
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seems like a simple adaptational thing to me, common ancestors more vulnerable to mutation--induced by viruses, free radicals, w/e--would be prone to decreased mitosis and lower fertility (certain of this, not certain they're more prone to death in that era)
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