chemistry folks: is it particularly common for isotopes to form bonds differently to each other, or do they all largely work the same except for extreme examples? a brief google said "they have the same electron count so probably" but that doesn't really answer the question
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Most of the stuff we use isotope measurement for(carbon dating, medical imaging) relies on the different isotopes behaving exactly the same chemically but decaying at different rates
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With that said, I want to say there's a few exceptions with how biological systems handle deuterium, possibly because it's significantly heavier than regular hydrogen.
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