Rajiv McCoy

@rajivmccoy

Assistant professor at Johns Hopkins studying human genome evolution, aneuploidy, and mosaicism.

Baltimore, MD
mccoy-lab.org
Joined September 2013
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  1. Pinned Tweet
    Sep 19
    Replying to

    I am recruiting PhD students through , as well as a postdoc. We study human evolutionary genomics. 👨‍👩‍👧‍👦🧬👩🏾‍💻📉 More info here:

    26 retweets 14 likes
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  2. Retweeted
    Oct 11

    I'm excited to share this perspective with , , , and RIKEN colleagues on the high potential for polygenic risk scores to improve health outcomes, but also raise health disparities given vast Eurocentric GWAS biases:

    2 replies 71 retweets 109 likes
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  3. Retweeted
    Oct 11

    Our manuscript on detecting and correcting for population variance structure in association studies is up! Joint work with Noah Zaitlen and Julien Ayroles. (1/n)

    2 replies 43 retweets 70 likes
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  4. Retweeted
    Oct 11

    I'm excited that our paper describing how we use human retinal organoids to determine the mechanisms generating cone photoreceptor subtypes is out!

    19 replies 62 retweets 222 likes
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  5. Retweeted
    Oct 10

    The UK Biobank genetic data paper is published today in Nature

    3 replies 125 retweets 227 likes
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  6. Retweeted
    Oct 10

    Sorry for the humblebrag, but proud to announce my 100th paper: a great collaboration with Ray Ming and many others to study the ultra-complex sugarcane genome: . Thanks to all that have helped me along the way & so many fun projects ahead for the next 💯!

    15 replies 49 retweets 269 likes
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  7. Retweeted
    Oct 9

    Great insight article by : "Just 5% of the human genome is subject to neutral evolution, but this process remains central to understanding the history of human migration across the Earth."

    2 replies 16 retweets 32 likes
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  8. Retweeted
    Oct 8

    JV elicits laughs when he says we must all be wondering how we’re alive with such erroneous cell division in early embryos. How? We think survival of the fittest cell

    1 reply 1 retweet 1 like
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  9. Retweeted
    Oct 8

    Chaotic embryos on PGT-A are likely result of tripolar segregation, where 1 cell segregates into 3, says JV

    1 reply 1 retweet
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  10. Retweeted
    Oct 5

    Estimating Neanderthal ancestry proportions from 23andMe data:

    1 reply 21 retweets 45 likes
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  11. Retweeted
    Oct 4

    I am very proud of this work on detecting a high rate of adaptive introgression between modern humans and Neanderthals associated with viruses led by and a commentary by and Fergal Case 1/n

    4 replies 39 retweets 92 likes
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  12. Retweeted
    Oct 1

    We've been working to remove and reduce barriers for anyone in high school on up to get into data science. The first part of our new effort is now up! Chromebook Data Science - a MOOC series on .

    17 replies 231 retweets 535 likes
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  13. Retweeted
    Sep 27

    Stunner alert. Transgenic mice with human CRH locus has delayed parturition. CRISPR deletion of LTR element restores wt gestation 👏 x 💯

    What made human gestation longer? An anthropoid-specific retroviral insertion regulates the expression of CRH, a placental protein associated with human birth timing; mice bearing this inertion have longer times
    32 retweets 75 likes
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  14. Retweeted
    Sep 27

    Very happy to see our work on mutation rates in owl monkeys (and primates in general) published! With , , , , and many others not on twitter (that I know of).

    5 replies 28 retweets 56 likes
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  15. Retweeted
    Sep 26

    Background selection has limited the rate of weak but not strong adaptation in human evolution! Really enjoyed collaborating with Lawrence Uricchio for this project. We also introduce a new MK test that accounts for BGS and segregating adaptive variants.

    2 replies 41 retweets 48 likes
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  16. Retweeted
    Sep 25

    Registration for the 11th conference on Chromosome Segregation and Aneuploidy meeting is now open! Great speakers, Great location, Great Science!

    18 retweets 20 likes
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  17. Retweeted
    Sep 21

    Please RT! The Dennis lab @ UC Davis is hiring a talented senior trainee (with M.S. or Ph.D.) to characterize zebrafish knockout mutants of neurodevelopmental disorder genes. A background in zebrafish genetics/development is a plus! If interested, email me: mydennis@ucdavis.edu

    3 replies 94 retweets 49 likes
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  18. Retweeted
    Sep 24

    I am super thrilled to share new work on the Omnigenic model with and ! We've been working on this for a while and we hope that you'll find it interesting!

    4 replies 111 retweets 160 likes
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  19. Retweeted
    Sep 23

    I had a fantastic time visiting the Center for Mechanisms of Evolution this past week . So excited to officially join the faculty in January!

    Hello ! Follow us for the latest updates on evolutionary cell biology happening at 's Center for Mechanisms of Evolution in Tempe, AZ.
    2 replies 9 retweets 35 likes
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  20. Retweeted
    Sep 23

    We tried to map variance QTLs...

    4 replies 41 retweets 85 likes
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  21. Retweeted
    Sep 22

    Very true. We do have many public datasets and repositories now. What we are really missing are legions of trained researchers and entrepreneurs to use and convert this data into more inventions and discoveries.

    Data sharing session with and Anna Barker. Wilbanks says big Gene expression database from Merck was accessed just twice in a decade by external scientists. The 'Field of Dreams' approach not best.
    11 replies 38 retweets 95 likes
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