Psychedelic Science Review

2005 Literature Review Proposes Serotonin Mediates the Effects of Estrogen: The authors argue that the serotonergic mediation of estrogen has important clinical implications and warrants further investigation. https://psychedelicreview.com/2005-literature-review-proposes-serotonin-mediates-the-effects-of-estrogen … #psychedelics #science

Vermont Rep. Brian Cina Introduces Bill to Decriminalize Psilocybin, Peyote, Ayahuasca, and Kratom: If passed and signed by Governor Phil Scott, the law will go into effect July 1, 2020. https://psychedelicreview.com/vermont-rep-brian-cina-introduces-bill-to-decriminalize-psilocybin-peyote-ayahuasca-and-kratom … #psychedelics #science

2000 Study Finds Estrogen + Progesterone Increases Cortical 5-HT2A Receptor Binding Potential in Postmenopausal Women: The hormone combination increased 5-HT2A binding potential over 20%. https://psychedelicreview.com/2000-study-finds-estrogen-progesterone-increases-cortical-5-ht2a-receptor-binding-potential-in-postmenopausal-women … #psychedelics #science

1995 Study Finds Estrogen Increases 5-HT2A Receptor Density in the Female Rat Brain: The increase was seen primarily in the cerebral cortex and the nucleus accumbens. https://psychedelicreview.com/1995-study-finds-estrogen-increases-5-ht2a-receptor-density-in-the-female-rat-brain … #psychedelics #science

Scientists Discover a New Cannabinoid in Cannabis sativa: Δ9-THCP: Tetrahydrocannabiphorol could account for the pharmacological properties of some cannabis varieties which are difficult to explain by the presence of THC alone. https://psychedelicreview.com/scientists-discover-a-new-cannabinoid-in-cannabis-sativa-delta-9-thcp … #psychedelics #science

The Medical University of South Carolina is Launching a Psychedelic Research Center: Scheduled to open in 2021, the new center will study the therapeutic potential of MDMA, psilocybin, DMT, and mescaline. https://psychedelicreview.com/the-medical-university-of-south-carolina-is-launching-a-psychedelic-research-center … #psychedelics #science

Eleusis’s Phase I Alzheimer’s Trial Finds Favorable Safety & Tolerability of LSD in Older Volunteers: There were no abnormalities or deviations in safety or cognitive outcome measures compared to the baseline data. https://psychedelicreview.com/eleusiss-phase-i-alzheimers-trial-finds-favorable-safety-tolerability-of-lsd-in-older-volunteers … #psychedelics #science

What is Kratom?: It is a plant that contains over 40 alkaloid and non-alkaloid compounds, some of which have analgesic and psychoactive properties. https://psychedelicreview.com/what-is-kratom  #psychedelics #science

Psychedelics as a Performance-Enhancer in Athletics: A look into the cognitive-enhancing effects of #psychedelics in sports https://psychedelicreview.com/psychedelics-as-a-performance-enhancer-in-athletics/ … #science #PED #cleansport @wada_ama

Single Ketamine Dose Could Help to Treat Problematic Drinking Behavior: New research suggests that ketamine can aid in reorganizing alcohol-related memories. https://psychedelicreview.com/single-ketamine-dose-could-help-to-treat-problematic-drinking-behavior … #psychedelics #science

Placebo-Controlled Study Finds Psilocybin Formulation is Safe and Well-Tolerated in Healthy Volunteers: The study used an investigational psilocybin formulation called COMP360 developed and produced by COMPASS Pathways. https://psychedelicreview.com/placebo-controlled-study-finds-psilocybin-is-safe-and-well-tolerated-in-healthy-volunteers … #psychedelics #science

Scientists Test the Effects of Inhaling Synthetic 5-MeO-DMT: Some changes occured to biomarkers for stress and inflammation. The subjective effects reveal more evidence of the entourage effect. https://psychedelicreview.com/scientist-test-the-effects-of-inhaling-synthetic-5-meo-dmt … #psychedelics #science

COMPASS Patent Highlights Importance of Crystallography in Psychedelic Drug Development: The scope and validity of this patent will depend on how x-ray diffraction data is interpreted. https://psychedelicreview.com/compass-pathwayss-new-patent-highlights-the-importance-of-x-ray-crystallography-in-psilocybin-drug-development … #psychedelics #science

Altered Oscillations: The Modulatory Effect of DMT on Brain Waves: A recent Nature paper provides novel insights into the neural correlates of the Breakthrough Experience associated with DMT. https://psychedelicreview.com/altered-oscillations-the-modulatory-effect-of-dmt-on-brain-waves … #psychedelics #science

Researchers at the Johns Hopkins University School of Medicine examined the effects of varying doses of #psilocybin and a single high dose of dextromethorphan (DXM) on cognitive abilities on humans. https://psychedelicreview.com/study-compares-the-effects-of-psilocybin-and-dxm/ … #psychedelics #science

Study Finds ALD-52, 1P-LSD, and 1B-LSD Are Prodrugs of LSD: Identifying and understanding prodrugs is an essential component of psychedelic drug research. https://psychedelicreview.com/study-finds-ald-52-1p-lsd-and-1b-lsd-are-prodrugs-of-lsd … #psychedelics #science

New Zealand’s Ministry of Health Approves LSD Microdosing Study: The study will examine the effects of microdosing LSD on the everyday lives of the participants. https://psychedelicreview.com/new-zealands-ministry-of-health-approves-lsd-microdosing-study … #psychedelics #science

New research provides insight into the debate centered around the brain's capacity to synthesize #DMT endogenously https://psychedelicreview.com/dmt-the-biosynthesis-debate/ … #science #neurochemistry #psychedelics

Machine Intervention: Psychedelics, Artificial Intelligence, and the Drug Discovery Process: A look into the promising potential of artificial intelligence in tackling unmet medical needs in mental healthcare. https://psychedelicreview.com/machine-intervention-psychedelics-artificial-intelligence-and-the-drug-discovery-process … #psychedelics #science