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propensive's profile
Jon Pretty
Jon Pretty
Jon Pretty
@propensive

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Jon Pretty

@propensive

Supporting Scala through professional training and open-source software. Responsible for Magnolia, Fury, Scala World and Functional Africa.

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propensive.com
Joined July 2010

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    1. Jon Pretty‏ @propensive 3 Apr 2020

      I wonder if, as a side effect of near-universal social-distancing, we will end up eliminating any other contagious viruses, such as flu strains. Or instead, will the new selective pressure cause more widespread mutations of these viruses?

      7 replies 2 retweets 22 likes
    2. Alan Johnson‏ @AlanJay1 4 Apr 2020
      Replying to @propensive

      I'm not sure about the selective pressure argument. The mutations happen regardless, and the best way to create chances for a superflu is more replications and exposures. So I expect we'll see suppression of all infectious diseases.

      1 reply 0 retweets 1 like
    3. Jon Pretty‏ @propensive 4 Apr 2020
      Replying to @AlanJay1

      My naïve assumption was that the absence of similar competing strains would give the mutations the space to survive long enough to spread, where normally they would be dominated by pre-existing strains. But it's guesswork on my part, and I really don't know how the dynamics work.

      1 reply 0 retweets 0 likes
    4. Alan Johnson‏ @AlanJay1 4 Apr 2020
      Replying to @propensive

      I'm not sure the extent to which viruses compete. In my mind, many viruses are probably complementary, as the immune system gets overwhelmed. There are plenty of replication factories to go around, and most viruses have strong prefs for cell type.

      2 replies 0 retweets 1 like
      Jon Pretty‏ @propensive 4 Apr 2020
      Replying to @AlanJay1

      Yes, it's beyond my current understanding. But I heard a virologist speaking on the radio about selective pressure resulting in mutations, and I worked back from that to try to understand why. Definitely don't assume any expertise on my part!

      1:30 PM - 4 Apr 2020 from Krakow, Poland
      • 1 Like
      • Alan Johnson
      0 replies 0 retweets 1 like

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