Thanks @profvrr @alandove @RichCondit @fakeDespommier . It's a great honor that our paper made it to #TWiV, it feels unreal! We now have a review out @Preprints_org discussing in more detail our hypothesis for the role of microbes in amyloid pathologieshttps://www.preprints.org/manuscript/201909.0273/v1 …
New episode of the #science #podcast This Week in Virology #TWiV 566: Chicken gumbo and a corona http://bit.ly/2m7S1FH the protein corona that surrounds virus particles, and a proofreading-impaired herpesvirus that produces quasispecies-like populationspic.twitter.com/uwwsUV9Z1y
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Bedankt, Twitter gebruikt dit om je tijdlijn te verbeteren. Ongedaan makenOngedaan maken
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You should definitely visit Umeå next summer Vincent. Especially around the 18-22th of June when the days are the longest. Sun will set around 11 p.m. and rise at 2 a.m. Also there is probably a queue of people waiting to show you the Stockholm archipelago, just let us know!
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Seconded! :)
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@alandove regarding the exposure of cryptic epitopes in the viral corona, this can also lead to autoimmune reactions. Many autoimmune diseases follow viral infections, this can be one mechanism.Bedankt, Twitter gebruikt dit om je tijdlijn te verbeteren. Ongedaan makenOngedaan maken
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dsDNA virus quasispecies? Or quasiquasispecies?
#TWiV 566, 37:20https://www.nature.com/articles/s41564-019-0547-x … -
Trimpert et al. write “We refer to highly diverse virus populations as quasispecies but recognize the controversy over the use of this term”, citing Holmes 2010https://www.sciencedirect.com/science/article/pii/S0022283610005243 …
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@alandove is right regarding anti-vaxxers in Sweden. Even though school is free and all that we still manage to cultivate a few home-grown misguided individuals here and there i.e. not exclusively an imported population.Bedankt, Twitter gebruikt dit om je tijdlijn te verbeteren. Ongedaan makenOngedaan maken
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@profvrr@alandove@RichCondit@fakeDespommier We believe that amyloid pathologies are neither "protein-only" nor "gain-of-toxic-function only". Aberrant membranes (including microbes) can physically precipitate proteins out of function. Opportunities for replacement therapy?Bedankt, Twitter gebruikt dit om je tijdlijn te verbeteren. Ongedaan makenOngedaan maken
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