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profshanecrotty's profile
Prof. Shane Crotty
Prof. Shane Crotty
Prof. Shane Crotty
@profshanecrotty

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Prof. Shane Crotty

@profshanecrotty

Vaccines and immune system scientist. Professor, La Jolla Institute for Immunology (LJI), a non-profit research institute. PhD not MD. Opinion ≠ medical advice

La Jolla, San Diego
lji.org/labs/crotty/
Joined March 2016

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    1. Prof. Shane Crotty‏ @profshanecrotty 8 Feb 2021

      Well, that's a nice surprise! What happens if you have had COVID infection before and you get a COVID vaccine?

      13 replies 127 retweets 392 likes
      Show this thread
    2. Prof. Shane Crotty‏ @profshanecrotty 8 Feb 2021

      Prof. Shane Crotty Retweeted Prof. Shane Crotty

      Some observations last week are summarized here:https://twitter.com/profshanecrotty/status/1356623349862989827?s=20 …

      Prof. Shane Crotty added,

      Prof. Shane Crotty @profshanecrotty
      What about vaccinating people who have already had COVID? I get this question a lot. New answers now! 🧵 https://www.nytimes.com/2021/02/01/health/have-you-had-covid-19-coronavirus.html …
      Show this thread
      3 replies 12 retweets 76 likes
      Show this thread
    3. Prof. Shane Crotty‏ @profshanecrotty 8 Feb 2021

      In a new pre-print by the excellent @McGuire_Lab , they report a big jump in neutralizing antibodies after a single COVID RNA vaccine immunization (Pfizer or Moderna). That is the same thing observed by @florian_krammer and the Sajadi labs.https://www.medrxiv.org/content/10.1101/2021.02.05.21251182v1 …

      4 replies 43 retweets 184 likes
      Show this thread
      Prof. Shane Crotty‏ @profshanecrotty 8 Feb 2021

      But, they also find that the immunized people now also make excellent neutralizing antibody responses to the South Africa variant! (B1351) A massive jump in neutralizing antibodies.pic.twitter.com/fg7AL0sDs8

      2:34 PM - 8 Feb 2021
      • 108 Retweets
      • 386 Likes
      • Marco Schön katalinwilkinson Shelby Bradford disruptive & sometimes cynical woman, J.D. Myrrh noa-witheringly Miriam van Gool Lynndelux thot leedurr
      18 replies 108 retweets 386 likes
        1. New conversation
        2. Prof. Shane Crotty‏ @profshanecrotty 8 Feb 2021

          First evidence that an immunization can elicit high neutralizing antibodies against the SA variant (B1351). I.e., the variant is not invisible to good human antibodies.

          14 replies 44 retweets 275 likes
          Show this thread
        3. Prof. Shane Crotty‏ @profshanecrotty 26 Mar 2021

          This work is now out in Science, with much more data. Important paper.https://science.sciencemag.org/content/early/2021/03/24/science.abg9175 …

          5 replies 23 retweets 55 likes
          Show this thread
        4. End of conversation
        1. Dog‏ @pss53 8 Feb 2021
          Replying to @profshanecrotty

          @Coronavirusgoo1

          0 replies 1 retweet 2 likes
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        1. New conversation
        2. Mikhail Kats‏ @mickeykats 8 Feb 2021
          Replying to @profshanecrotty

          It's also partially protective against SARS?!

          1 reply 0 retweets 3 likes
        3. BiotechObserver‏ @BiotechObserver 8 Feb 2021
          Replying to @mickeykats @profshanecrotty

          If anyone brings it back it will only infect 800 people this time instead if 8000

          0 replies 0 retweets 0 likes
        4. End of conversation
        1. Dr Ilham Abuljadayel‏ @ilhamabuljadaye 8 Feb 2021
          Replying to @profshanecrotty

          This is only observed in covid19 vitctims?! Great news

          0 replies 0 retweets 1 like
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        1. WryWryWry‏ @WryWryWry3 8 Feb 2021
          Replying to @profshanecrotty

          Any conclusion on CD8+ and T-cell immunity? Will there be a study on that at some point as well to measure the role it plays in an obviously multi-layered very immune response the vaccines have against SARS-COV-2?

          0 replies 0 retweets 4 likes
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        1. New conversation
        2. Persistenza‏ @PersistenzaPaga 8 Feb 2021
          Replying to @profshanecrotty

          Can someone help explain to me why this would be? If prior infection from earlier strain does not protect adequately against B1351, and vax does not protect adequately against B1351 (as some have been positing, following yesterday's news) how does 1+1=3?

          1 reply 0 retweets 2 likes
        3. PastaMonkey‏ @monkey_pasta 8 Feb 2021
          Replying to @PersistenzaPaga @profshanecrotty

          Neither of those are true. Vax does protect against B1351. The efficacy reduction has only been in mild disease prevention, which means you get a sore throat instead of nothing. Also, there is no evidence that prior infection doesn’t protect. Again, you may get a runny nose.

          1 reply 0 retweets 6 likes
        4. Show replies
        1.  Ⓜ️ark Holton‏ @MarkHolton 8 Feb 2021
          Replying to @profshanecrotty

          @EricTopol FYI 👆

          0 replies 0 retweets 0 likes
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