I've been calling this the 'massively pleiotropic mutation model' for about 17 years, but whatever. https://www.theatlantic.com/science/archive/2017/06/its-like-all-connected-man/530532/ …
Well, both. Pleiotropic, but 'massively' in the sense of polygenically
-
-
(Hmm: Pleio-tropic means 'many effects', one gene many effects. The 'massively' --> approx., a great many genes are very pleiotropic.)
-
(Always liked the 'watershed analogy' of multiple downstream gene-biochem effects, on page 26 of Keller Miller 2006) http://matthewckeller.com/Keller_Miller_BBSPreprint_RevWTables.pdf …
End of conversation
New conversation -
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.