From gwas? In 20k people, .001 SNPs will be almost all non replicable. Only carried by 20 people in the sample & hi call error rates
Rare mutations explain at least half the heritability of IQ: New GREML-MS data on DNA from 20,032 people -- Lars Penke at #HBES2017pic.twitter.com/yqHc7Wx9rz
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Greml-ms, and only the 7k unrelateds. SEs are large, true. Consistent with kin-based data, Evans et al. though. Still concerned?
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These are variance components so we can't say.
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Is this from "Genomic analysis of family data reveals additional genetic effects on intelligence and personality" http://biorxiv.org/content/early/2017/02/06/106203 … ?
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wonder if bottom IQ half has higher R2 than top half, looking just w/in those two samples. As most mutations bad, would suspect so.
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