What percentage of studies linking candidate genes to behavioral traits, clinical/psychological diagnoses and brain function (e.g., fmri) do you think are false positives (FP) or overestimate the true ES by orders of magnitude?
Does anyone in behavior genetics still take candidate genes studies seriously? I thought everyone had abandoned them in favor of polygenic scores based on thousands of genetic loci.
-
-
Many / most people I know don't take them seriously because GWAS suggests that most individual genetic effects are (very) small. But papers on the topic are still being published, so I was interested in people's opinions.
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
Aren't there only 24000 genes in a human? How could each trait depend on thousands?
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.