"We bring the model to the data for the whole world economy at a 1° × 1° geographic resolution. … Fully liberalizing migration would increase welfare about threefold." https://www.journals.uchicago.edu/doi/abs/10.1086/697084 …
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The paper makes no such assumptions as far as I can see, although I'm not sure exactly what "cultural inertia" denotes in this context. Generally, economics does not invoke a blank slate assumption.
The whole 'human capital' model in econ implicitly assumes zero heritability, or a blank slate...
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There is no assumption that heritable traits don't affect human capital, either directly or indirectly. And there are lots of papers on mechanisms underlying intergenerational human capital dynamics which explicitly model genetics, e.g., https://www.sciencedirect.com/science/article/pii/S0167629614000253 …
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