This thread about math reminds me of a fallacy I frequently see in systems design, where some people believe that, because they've created simple primitives, the resultant systems that are built on top will be simple and easy to reason about.
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I have the sense that you're alluding to some deeper truth about how the world works. Something like: system design sometimes involves a true complex system. When that happens, good intuitions stop working. Does my interpretation make any sense to you?