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  1. Prikvačeni tweet
    7. ruj 2019.

    Excited to announce that my lab is moving this fall to . We develop new biotechnologies (and not just CRISPR-Cas!) to control brain and immune cell function for improving human health. Hiring at all levels (postdocs, grad students, RAs) -

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  2. proslijedio/la je Tweet
    prije 17 sati

    ZipSeq from the Krummel lab ( ) prints spatially-patterned barcodes onto live cells within intact tissues. After dissociation and scRNA-seq, cells can be mapped to their original location!

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  3. prije 19 sati

    umm...I wish. Better pick up the pace 😅

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  4. 3. velj

    2019-nCov coronavirus in - probably from bats and 80% sequence identity to SARS/uses the same ACE2 receptor for cell entry

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  5. proslijedio/la je Tweet
    23. sij

    Many biologists are interested in how well RNA and protein expression correlate. We confirmed that they have middling correlation on average (~0.5). But the scope of these data let us ask this on a per-gene level across many tissue lineages. (3/13)

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  6. proslijedio/la je Tweet
    22. sij

    Happy to share our paper showing that temperate phages can drive the loss of CRISPR-Cas system. Great collaborative effort with

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  7. proslijedio/la je Tweet
    15. sij

    The first lab brain tumor paper is out today! . We began the project wanting to understand the role of meningeal lymphatics in brain tumor. To our surprise, when we expanded the lymphatics with VEGF-C, mice could no longer grow tumors!

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  8. proslijedio/la je Tweet
    13. sij
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  9. 12. sij

    Hot take - biology is the only one with truly difficult ideas. That’s why everyone is trying to apply math, physics, ML, etc to understand biological principles and behavior

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  10. proslijedio/la je Tweet

    We are proud to partner with and to bring you the Global Conference this February in D.C. Come learn and mingle with brightest minds in the research community. Register now:

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  11. proslijedio/la je Tweet
    7. sij

    Thrilled to be joining this amazing team! Look forward to working with founders who will change the future of healthcare and make it work better for patients 👊🏼

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  12. 6. sij

    Are we that bad at this type of recall? I’ve only done mouse behavior, and that takes a lot of trials...I wonder how well an average human with similar training would fare relative to the chimps

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  13. proslijedio/la je Tweet
    20. kol 2019.

    Excited to release preprint of 2.0 by & Joyce Samson.

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  14. proslijedio/la je Tweet
    3. sij

    2020 will be the decade of cell therapy and genome engineering

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  15. proslijedio/la je Tweet
    27. pro 2019.

    Finally out: Scalable and cost-effective ribonuclease-based rRNA depletion for transcriptomics. Cheaper/better than commercial rRNA depletion kits. Congrats to Yiming and ⁦⁩ for leading this work. ⁦

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  16. proslijedio/la je Tweet
    20. pro 2019.

    Single-cell RNA-seq led to a surprising model of alternative splicing: individual cells make one isoform or the other, but rarely both in one cell. Carlos Buen Abad Najar, working with Nir Yosef and me, shows that this is an artifact of low mRNA recovery.

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  17. proslijedio/la je Tweet
    18. pro 2019.

    Ultra-high throughput scRNA-seq from Christoph Bock's lab! Combines combinatorial barcoding with droplet microfluidics to sequence >150,000 cells on a single lane:

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  18. proslijedio/la je Tweet
    16. pro 2019.

    Nice new work for targeted randomization in mammalian cells using T7RNAP-deaminase fusions!

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  19. proslijedio/la je Tweet

    So we learned some details about George Church's DNA dating app -its a startup company called Digid8 -funded by Church and unnamed others -prevent dates between carriers of same recessive mutation -WILL NOT block dates for people carrying dominant genes

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  20. 11. pro 2019.

    Does this work with multiple fragments? Fragments of different length? For one insert, this makes a lot of sense because the no insert control always has such high background. Also, don’t buy Gibson mix...make it

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  21. proslijedio/la je Tweet
    9. pro 2019.

    Excited to share our newly published method we call Probe-Seq! With it, you can easily isolate (potentially) any cell type from (potentially) any organism and perform cell type specific bulk RNA-Seq! We used mouse, human, Drosophila, and chick as a proof of concept.

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