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Prikvačeni tweet
I'm excited to share my paper on the mating preferences of selfish sex chromosomes, now online at Nature! This will be a short thread on the main results. 1/ https://rdcu.be/bFE8c
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Pavitra Muralidhar proslijedio/la je Tweet
Congratulations to
@JLosos - the well-deserving recipient of the 2019 Sewall Wright Award from the@ASNAmNat https://www.journals.uchicago.edu/doi/abs/10.1086/706257 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Pavitra Muralidhar proslijedio/la je Tweet
Our AAV paper published in Science on Thanksgiving, 4+ years with
@PierceOgdenJ,@samsinai,@geochurch, continuing now at@dyno_tx, here’s how: including twists, turns, surprises, and many people to thank along the way!https://science.sciencemag.org/content/366/6469/1139 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Pavitra Muralidhar proslijedio/la je Tweet
New preprint, on how *aggregate* recombination modulates: (a) variance in the genetic relatedness of relatives; (b) how rapidly selection purges introgressed DNA. Turns out (a) and (b) are... related! w/
@natebedelman@pavitra451@DrMANowak http://doi.org/10.1101/846147 1/2pic.twitter.com/dX7IEG3wiV
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Pavitra Muralidhar proslijedio/la je Tweet
Erin Calfee on admixture and selection in Africanized honey bees: Honey bees not native to Americas - here they are admixed ‘feral’ populations of European origin, and in the 50s African bees were brought over to increase genomic fitness. They escaped!
#bapgxviiiPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Pavitra Muralidhar proslijedio/la je Tweet
Thrilled to have this out- If you want to use QuIBL on your system, please get in touch!https://twitter.com/natebedelman/status/1189977406842363905 …
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Pavitra Muralidhar proslijedio/la je Tweet
Our project on genomic architecture, introgression in Heliconius is out! We (
@paulbfrandsen@MichaelMiyagi@WTF_R_species@mel_rosina@SVBelleghem et al) build on work in Heliconius and other systems to show how important hybridization is in evolution. http://tinyurl.com/y5fmqya6 1/Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Pavitra Muralidhar proslijedio/la je Tweet
Probably the most unexpected discovery of my career: Massive gene amplification on a newly formed Y chromosome! Great teamwork with my lab!https://www.nature.com/articles/s41559-019-1009-9 …
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Pavitra Muralidhar proslijedio/la je Tweet
New preprint, in which we try to understand Fisher's model of sexual selection. With
@pavitra451 and David Haig.https://www.biorxiv.org/content/10.1101/815613v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Pavitra Muralidhar proslijedio/la je Tweet
(Thread) Here’s my new preprint, with
@Graham_Coop, on genetic privacy in genealogy databases that allow user uploads. (1/n)https://www.biorxiv.org/content/10.1101/798272v1 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Pavitra Muralidhar proslijedio/la je Tweet
"The unifying theme of Hartl’s broad impacts on transmission, population, evolutionary, and medical genetics has been the combination of theoretical insights with cutting-edge experimental techniques."http://bit.ly/2S44RkA
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Pavitra Muralidhar proslijedio/la je Tweet
In our new paper, just out in PNAS, we derive a surprisingly simple formula that relates the expected diversity of a metastasis to the diversity in the pool of seeding cells. Alex Heyde
@jgreiter@naxerova http://www.pnas.org/content/early/2019/06/24/1819408116 …pic.twitter.com/0XtQS06vqO
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Pavitra Muralidhar proslijedio/la je Tweet
News & Views: Why have females of some species evolved mating preferences for harmful male traits? A Nature paper models how these preferences can evolve if versions of genes that contribute to these traits have beneficial effects when present in females.https://go.nature.com/2Wu0wwb
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For an excellent summary of the paper, please check out the News and Views commentary by Mark Kirkpatrick! 12/https://www.nature.com/articles/d41586-019-01714-5 …
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Thank you for reading! Please let me know if you have any questions. 11/11
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The picture this theory paints, of one sex chromosome urging its bearer to mate with that individual, the other sex chromosome saying "no, that one!", and the autosomes saying "neither!", reminded me of this wonderful passage from WD Hamilton: 10/pic.twitter.com/vDka6CnRxV
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The logic also extends to any genetic element that can influence its host's mating behavior and shows sex-specific or sex-biased transmission—mitochondria, intra-cellular parasites like Wolbachia, and even microbiota are all vulnerable! 9/
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I've focused on female mate choice so far, but male mate choice plays an important role in many species! For male mate choice, simply flip the pattern: e.g., a Y chromosome in male mate choice behaves the same as the W in female mate choice. 8/
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Z-linked mate preferences for male-beneficial, female-costly traits evolve more readily than X-linked preferences for female-beneficial, male-costly traits, for subtle reasons explained in the paper. So, ZW species are especially prone to selfish sex-linked mate preferences! 7/
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This process applies to X and Z chromosomes too! They are sex-biased chromosomes, but not sex-specific like the W. Therefore, their selfish interests are slightly weaker. Note that the X cares more for female fitness (like the W) but the Z cares more for male fitness. 6/
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If the W-linked preference is strong enough, its spread eventually causes the trait to become advantageous (its mating advantage exceeding its viability cost). The trait then spreads. This is possible for traits that severely reduce male survival—e.g. by as much as 80%! 5/
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