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paulg's profile
Paul Graham
Paul Graham
Paul Graham
Verified account
@paulg

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Paul GrahamVerified account

@paulg

paulgraham.com
Joined August 2010

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    Paul Graham‏Verified account @paulg 26 May 2015

    You don't discover penicillin by asking "What are the applications of bread mould?"

    5:46 PM - 26 May 2015
    • 948 Retweets
    • 890 Likes
    • Jerry Crockett WakaTime Rebecca Davies Rose Henderson Andrew Pantyukhin Claude Rechtmacher Josh Carpenter Timothy Asiimwe Ali @ Streamlabs
    37 replies 948 retweets 890 likes
      1. New conversation
      2. Manjari Narayan‏ @NeuroStats 26 May 2015
        Replying to @paulg

        @paulg @pmarca This reminds me of brilliant yet serendipitous discovery of chemotherapy drugs. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150444/ …pic.twitter.com/L0R0ioPole

        1 reply 15 retweets 36 likes
      3. 1 more reply
      1. New conversation
      2. Jim Gray‏ @grayj_ 26 May 2015
        Replying to @paulg

        @paulg @Swizec Mostly you discover penicillin via constant work with bacteriological cultures + correctly spotting "that's funny" events.

        1 reply 1 retweet 5 likes
      3. Jim Gray‏ @grayj_ 26 May 2015
        Replying to @grayj_

        @paulg @Swizec The major competing models being Edison (iterate over parameter space) or Kepler (have tons of data & do good analysis).

        0 replies 1 retweet 10 likes
      4. End of conversation
      1. Jeff  ♨️ Darcy‏ @Obdurodon 27 May 2015
        Replying to @paulg

        @paulg @strlen You discover it by pivoting until your MVP disrupts the herbalist cartel and gets you a billion-dollar valuation, of course.

        2 replies 2 retweets 4 likes
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      1. Sam S. Lee‏ @OpenNotion 27 May 2015
        Replying to @paulg

        I hope the #data community takes this to heart RT @paulg you don't discover penicillin by asking "what are the applications of bread mold?"

        0 replies 2 retweets 4 likes
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      1. Gabriel Gasparolo‏ @ggasp 28 May 2015
        Replying to @paulg

        You don’t discover penicillin by asking “What are the applications of bread mould?” (via @paulg)

        0 replies 2 retweets 1 like
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      1. Laurence Pearl  🔥#FBPE‏ @laurencepearl 27 May 2015
        Replying to @paulg

        @paulg @S_M_Lea but you do discover chemical chirality by trying to understand how wine goes off - or at least Pasteur did

        0 replies 1 retweet 1 like
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      1. New conversation
      2. Pierre Chapuis‏ @pchapuis 26 May 2015
        Replying to @paulg

        @paulg Basically, yes you do. 32 years before Fleming. http://en.wikipedia.org/wiki/Ernest_Duchesne …

        1 reply 0 retweets 5 likes
      3. Pierre Chapuis‏ @pchapuis 26 May 2015
        Replying to @pchapuis

        @paulg (The reasoning was: "Tap water bacteria kill mold. Can we make it work the other way around?")

        0 replies 0 retweets 0 likes
      4. End of conversation
      1. Mayur Rustagi‏ @mayur_rustagi 26 May 2015
        Replying to @paulg

        @paulg How about if I have very strong conviction that bread mould is valuable & keep trying to apply it everywhere :)

        0 replies 0 retweets 2 likes
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      1. Ethan Nicolai‏ @VaedaSynapse 26 May 2015
        Replying to @paulg

        @paulg you get it by carelessness, orange peels left to mold in the trash, an open petri dish, a weekend and eyes to see something more :)

        0 replies 0 retweets 2 likes
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      1. Farzad Mostashari‏Verified account @Farzad_MD 28 May 2015
        Replying to @paulg

        Hope to capitalize on random luck? #SV_Startup “@paulg: You don't discover penicillin by asking "What are the applications of bread mould?"”

        0 replies 0 retweets 1 like
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      1. Rob Booker‏ @robbooker 27 May 2015
        Replying to @paulg

        @paulg @polemitis Oh crap then how are we ever going to discover penicillin now

        0 replies 0 retweets 1 like
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      1. Emin Gün Sirer‏Verified account @el33th4xor 27 May 2015
        Replying to @paulg

        @paulg @fermin_ordaz And we don't do academic research on a consignment basis, the way many lawmakers think it works or should work.

        0 replies 0 retweets 1 like
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      1. John Torous, MD MBI‏ @JohnTorousMD 26 May 2015
        Replying to @paulg

        . @paulg -Great quote on need for #mobilehealth #mhealth research and not just consumer apps!

        0 replies 1 retweet 0 likes
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      1. Brian Chu‏ @brrrianchu 26 May 2015
        Replying to @paulg

        @paulg unfortunately how a lot of bitcoin ideas are generated (by people asking themselves this)

        0 replies 0 retweets 1 like
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      1. Startup Dreams‏ @Startup_Dreams 26 May 2015
        Replying to @paulg

        @paulg You discover it by wondering how to solve the problem that is presented. Then, you go about stumbling your way to the solution?

        0 replies 0 retweets 1 like
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      1. Shadyrock‏ @ShadyrockSports 26 May 2015
        Replying to @paulg

        @paulg Mold

        0 replies 0 retweets 1 like
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