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paulg's profile
Paul Graham
Paul Graham
Paul Graham
Verified account
@paulg

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Paul GrahamVerified account

@paulg

paulgraham.com
Joined August 2010

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    Paul Graham‏Verified account @paulg 11 May 2020

    24% of Italians are smokers, but of 441 patients admitted to a hospital in Parma for Covid-19, only 5% were. Possible explanation: Smoking could make the immune system "tolerant of a continuous inflammatory insult."https://www.medrxiv.org/content/10.1101/2020.05.05.20092015v1.full.pdf+html …

    3:41 AM - 11 May 2020
    • 90 Retweets
    • 663 Likes
    • AA allen abraham Chris McCormick pump respecter Wrath Of Gnon insert name Roxanne Underwood Hendricks Ken MacPherson Intelligent Investor
    69 replies 90 retweets 663 likes
      1. New conversation
      2. Andrei Kucharavy‏ @andrei_chiffa 11 May 2020
        Replying to @paulg

        Or they could have declared not to be smoking to avoid being triaged into the "no ventilator/no resuscitation" category.

        4 replies 0 retweets 44 likes
      3. Charles Curran‏ @charliebcurran 11 May 2020
        Replying to @andrei_chiffa @paulg

        That was the hypothesis when the data about smokers being underrepresented in hospitalizations started coming out of China but it looks to be mirrored in Germany/France/US CDC data

        1 reply 0 retweets 5 likes
      4. Show replies
      1. Charles Curran‏ @charliebcurran 11 May 2020
        Replying to @paulg

        Have been really curious about this anomaly since coming across this:https://www.qeios.com/read/Z69O8A.13 

        0 replies 0 retweets 2 likes
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      1. edoardottt 👹‏ @edoardottt2 11 May 2020
        Replying to @paulg

        I'm Italian and I smoke. But it's obvious. Don't do it only for the virus. Keep your lungs clean.

        0 replies 0 retweets 0 likes
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      1. Vikram Aggarwal‏ @AggersV 11 May 2020
        Replying to @paulg

        Basically no one has a clue yet

        0 replies 0 retweets 25 likes
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      1. Cassandra‏ @star95011 11 May 2020
        Replying to @paulg

        💐❣️🤍☀️Happy Monday 💙❣️💗Paul🤍💐love and blessings to you and yours💗#TwitterFamily 💙☀️

        0 replies 0 retweets 0 likes
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      1. New conversation
      2. Philippe MÉDA  🇪🇺‏ @icopilots 11 May 2020
        Replying to @paulg

        21 Patients were smokers. You’re obviously educated enough not to try to apply statistical and correlation reasoning on such a sample. Treating medical as computer science is very OK.

        2 replies 0 retweets 7 likes
      3. Nassim Dehouche‏ @ndehouche 11 May 2020
        Replying to @icopilots @paulg

        Nassim Dehouche Retweeted Nassim Dehouche

        It's been observed on larger samples too, in all countries.https://mobile.twitter.com/ndehouche/status/1254092657262903297 …

        Nassim Dehouche added,

        Nassim Dehouche @ndehouche
        Replying to @robertwiblin @paulg
        It doesn't explain why the proportion of smokers with CoVid is 5 to 10 fold lower than the proportion of smokers in the general population. The same pattern has been observed in France, the US and China. pic.twitter.com/DUyxsRGb2f
        1 reply 0 retweets 4 likes
      4. Show replies
      1. Josh, Stranger in a strange land.‏ @Jballard11Josh 11 May 2020
        Replying to @paulg

        Non smokers generally live longer. Long enough to be in the major at risk >80 YO age group....

        0 replies 1 retweet 46 likes
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      1. Nassim Dehouche‏ @ndehouche 11 May 2020
        Replying to @paulg

        Nassim Dehouche Retweeted Nassim Dehouche

        It could be that smokers simply die more and earlier of CoVid and thus are underrepresented among the hospitalized. OTOH Nicotine is known to inhibit ACE2, the receptor of the virus. https://mobile.twitter.com/ndehouche/status/1249766111907704833 … This deserves some serious, full-time scrutiny.

        Nassim Dehouche added,

        Nassim Dehouche @ndehouche
        Replying to @KlausKblog
        "A recent study has confirmed that severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) uses severe acute respiratory syndrome coronavirus (SARS‐CoV) receptor angiotensin‐converting enzyme 2 (ACE2) for host cell entry." https://www.ahajournals.org/doi/10.1161/JAHA.120.016219 … 👍
        0 replies 0 retweets 8 likes
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