Hard to find good stuff online but WWII Committee on Medical Research probably has useful lessons. In very short order, figured out how to scale penicillin production, found better malaria antivirals (including chloroquine!), huge improvements in blood transfusions/replacements…
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These programs were *fast*. (Just over one year from formation of board to coordinate work on malaria to getting the first therapeutics shipped.)
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There's lots of precedent for rapid, successful, directed medical research led/coordinated by US Government.
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There might be better coverage elsewhere but best I've found is in medical chapters of https://www.amazon.com/Scientists-against-James-Phinney-Baxter/dp/0262520125 ….
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Bush also covers some of it in his memoir: https://www.amazon.com/Pieces-action-Vannevar-Bush/dp/B0006CAJ44 ….
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Replying to @patrickc
It's a hard book to find cheap copies of but fortunately
@gwern hosts a pdf https://www.gwern.net/docs/history/1970-bush-piecesoftheaction.pdf …3 replies 1 retweet 18 likes
Ah, awesome. Thank you @gwern. 
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Replying to @patrickc @hamandcheese
NP. Don't forget to check Libgen too - I don't dare host a lot of books.
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