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patrickc's profile
Patrick Collison
Patrick Collison
Patrick Collison
Verified account
@patrickc

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Patrick CollisonVerified account

@patrickc

Fallibilist, optimist. Stripe CEO.

patrick@stripe.com
patrickcollison.com
Joined April 2007

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    Patrick Collison‏Verified account @patrickc Sep 17

    Roommate got a MinION DNA sequencer. It’s about the size of an iPhone and costs less than the iPhone Xs. The future is pretty cool.pic.twitter.com/6U8aQcqNZH

    7:33 AM - 17 Sep 2018
    • 270 Retweets
    • 1,193 Likes
    • Fi Sri Kosuri Pekka Varmanen Sonny Fossheimer Ryo Negishi Oxford Nanopore HumpBack Whale 🐳🌊 Alaskeh A*F♡AI 😴👑👗🗿Get Offa Me
    35 replies 270 retweets 1,193 likes
      1. Dylan Althouse  🌏‏ @MrDylanAlthouse Sep 17
        Replying to @patrickc

        If it has a 3.5 mm headphone jack, double win.

        0 replies 2 retweets 16 likes
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      1. New conversation
      2. Yasmeen‏ @YasmeenRoumie Sep 17
        Replying to @patrickc

        at first I read this as "minion DNA sequencer"pic.twitter.com/1r2jhe0A5V

        1 reply 2 retweets 41 likes
      3. 2 more replies
      1. Scott Raney‏ @sraney Sep 17
        Replying to @patrickc

        That is awesome. I remember getting excited when my roommate brought home a foosball table. My how times have changed...and the future is pretty cool!

        0 replies 1 retweet 6 likes
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      2. Ian Mellett‏ @dodgrile Sep 17
        Replying to @patrickc

        At risk of asking a stupid / obvious question - what can you do with it?

        1 reply 0 retweets 6 likes
      3. Nathan Archer‏ @NathanArcheRNA Sep 18
        Replying to @dodgrile @patrickc

        Sequence DNA, potentially also RNA, with very long read lengths. Aims to replace large, immobile, and more expensive "shotgun" sequencers - but has some way to go in quality and amount of data. Awesome tech.

        1 reply 0 retweets 4 likes
      4. Ian Mellett‏ @dodgrile Sep 18
        Replying to @NathanArcheRNA @patrickc

        Thanks! So... encoding / decoding a large amount of data directly into the DNA / RNA string? I'm fascinated, but I feel like I'm enormously under-educated on the potential use cases here :)

        1 reply 0 retweets 0 likes
      5. Nathan Archer‏ @NathanArcheRNA Sep 18
        Replying to @dodgrile @patrickc

        It's useful for reading the DNA or RNA directly. Has been used to identify strains of ebola in the field. Longer term, having longer reads from DNA means more accurate alignment to known sequences and better identification of new genes.

        1 reply 0 retweets 1 like
      6. Ian Mellett‏ @dodgrile Sep 18
        Replying to @NathanArcheRNA @patrickc

        twitter is a pain sometimes, but you can't beat it for this kind of stuff. Thanks, appreciate the insight :)

        0 replies 0 retweets 1 like
      7. End of conversation
      1. New conversation
      2. 𝕘𝕚𝕕𝕖𝕠𝕟‏ @ghod Sep 17
        Replying to @patrickc

        If your roommate putting their coworkers they don’t like into a video game?

        2 replies 0 retweets 12 likes
      3. 𝕘𝕚𝕕𝕖𝕠𝕟‏ @ghod Sep 17
        Replying to @ghod @patrickc

        Is* 🙃

        0 replies 0 retweets 0 likes
      4. End of conversation
      1. New conversation
      2. Raphaël Pinson‏ @raphink Sep 18
        Replying to @patrickc

        What chip is it? Does it output files compatible for upload to sites like FTDNA/MyHeritage/GedMatch?

        1 reply 1 retweet 2 likes
      3. James Ferguson‏ @Psy_Fer_ Sep 19
        Replying to @raphink @patrickc

        minION is more a dongle/device, with a usb plug to a computer. It's a bit different to the technologies employed by my heritage/Etc, in that it can sequence every letter in your genome, not just targeted regions. Thus the computation is more complicated. This will improve in time

        1 reply 0 retweets 0 likes
      4. Raphaël Pinson‏ @raphink Sep 19
        Replying to @Psy_Fer_ @patrickc

        So it's a full genome sequencing then?

        1 reply 0 retweets 0 likes
      5. James Ferguson‏ @Psy_Fer_ Sep 19
        Replying to @raphink @patrickc

        Whole* Genome Sequencer (WGS). Yes.

        1 reply 0 retweets 0 likes
      6. Raphaël Pinson‏ @raphink Sep 19
        Replying to @Psy_Fer_ @patrickc

        So I'm guessing it should be possible to extract specific SNPs from the result to generate CVS files compatible with the testing companies, or am I missing something?

        1 reply 0 retweets 0 likes
      7. James Ferguson‏ @Psy_Fer_ Sep 19
        Replying to @raphink @patrickc

        Yes, but the tech and bioinformatics for the tech, is still developing. So, eventually, yes, but the power of this tech is not so much SNPs, and SNPs are not really the be all and end all of genomics. The current tech has just been good at them, thus why they have been overused

        0 replies 0 retweets 4 likes
      8. End of conversation
      1. San‏ @vicentes Sep 17
        Replying to @patrickc

        What is she/he using it for ?

        0 replies 0 retweets 2 likes
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      1. New conversation
      2. telospolis‏ @telospolis Sep 17
        Replying to @patrickc

        have wanted this for soooooo long! anyhow! every flow cell cost 250 or something like that!

        1 reply 0 retweets 0 likes
      3. Jurgis‏ @sjurgis Sep 17
        Replying to @telospolis @patrickc

        Kinda worth it if you are outside US - 23andMe and Acenstry has crazy shipping fees. But on a flip side, there ain't much paid or free sites where you can import your DNA data.

        1 reply 0 retweets 1 like
      4. telospolis‏ @telospolis Sep 17
        Replying to @sjurgis @patrickc

        23 and me , ancestry are not in the same game as miniIon. 23 and me only looks at gene expression, this thing could could technically sequence the whole DNA *t&c apply.

        1 reply 0 retweets 0 likes
      5. Nathan Archer‏ @NathanArcheRNA Sep 18
        Replying to @telospolis @sjurgis @patrickc

        23&me doesn't look at expression. It looks at SNPs. Personal whole genome sequencing is available from some companies already for a few hundred quid.

        1 reply 0 retweets 1 like
      6. telospolis‏ @telospolis Sep 18
        Replying to @NathanArcheRNA @sjurgis @patrickc

        you are right they look at SNPs. idk, why i said gene expression! idk. maybe because, i was thinking about micro arrays. for gene expression we use micro arrays and 23 and me type SNPs also use Micro arrays.

        0 replies 0 retweets 0 likes
      7. End of conversation

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