1LIFEMAX

@onelifemax

Motivation, inspiration, knowledge, science, philosophy, health/fitness/wellness, entrepreneurship, growth, business/investing, books and the good life.

Live life to the max.
Vrijeme pridruživanja: studeni 2014.

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  1. Prikvačeni tweet
    29. tra 2015.

    Arthur Rock on what it takes to start a new company (1984):

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  2. proslijedio/la je Tweet
    2. velj
    Odgovor korisnicima

    "When dealing with complex systems governed by feedback loops, circular causality, and large-scale setpoints, the control structures (causes) are not obvious and hard to determine; they are often distant, both spatially and temporally, from the event in question."

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  3. proslijedio/la je Tweet
    2. velj
    Odgovor korisnicima

    discovered a very efficient way to control system-level outcomes: rewriting large-scale homeostatic setpoints and letting the system regulate to them, instead of micromanaging all of the myriad low-level details to achieve the desired outcome in the face of novel circumstances."

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  4. proslijedio/la je Tweet
    2. velj
    Odgovor korisnicima

    "Recent advances in information theory confirm that the most salient causes in a system are not always found at the lowest level of organization (in this field, often thought to be subcellular biochemistry). "The widespread prevalence of modularity reveals that evolution

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  5. proslijedio/la je Tweet
    2. velj
    Odgovor korisnicima

    Translates & -Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs "It might provide an explanation for how metabolic changes can both positively or negatively influence opposing gene programs in the same cell type."

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  6. proslijedio/la je Tweet
    1. velj
    Odgovor korisnicima i sljedećem broju korisnika:

    But different teas have different unique bioactive compounds beneficial for health via different mechanisms, for example from green tea, from oolong tea & from Pu-erh tea:

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  7. proslijedio/la je Tweet
    1. velj
    Odgovor korisnicima i sljedećem broju korisnika:

    Time to suggest something better than CRM's, namely YFM's (): Black tea derived Theaflavin 3-gallate () mimics hypothalamic youth factor and protects against aging-associated physiological decline.

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  8. proslijedio/la je Tweet
    24. sij

    “At some point the word ‘strategy’ becomes a euphemism for procrastination." —Peter Thiel

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  9. proslijedio/la je Tweet
    29. sij
    Odgovor korisniku/ci

    "These prospective, community-based data suggest that deficiency is associated with increased CVD risk, above & beyond established CV risk factors." "Vitamin D supplementation reduced the risk of cancer death by 16%. "

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  10. proslijedio/la je Tweet
    27. sij
    Odgovor korisnicima i sljedećem broju korisnika:
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  11. proslijedio/la je Tweet
    27. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    Interesting concept: Preclinical Reversal of by FDA-Approved Compound () that Transforms Cholesterol into an Anti-Inflammatory “Prodrug”.

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  12. proslijedio/la je Tweet
    25. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    It will be a combination & why wouldn't it be natural molecules? After all, in a period the body produces what it needs to keep us young. "We hypothesize that altered intensities of a few morphogenic pathways account for most/all the phenotypes of aging."

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  13. proslijedio/la je Tweet
    25. sij
    Odgovor korisnicima

    "What has to prove true for this to work?"

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  14. proslijedio/la je Tweet
    25. sij
    Odgovor korisnicima

    "Real —in companies and in our lives—is created through hundreds of everyday decisions about where we spend our resources. As you’re living your life from day to day, how do you make sure you’re heading in the right direction? Watch where your resources flow." RIP

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  15. proslijedio/la je Tweet
    25. sij
    Odgovor korisniku/ci

    "I’ve changed some ideas as I’ve learned more. Uber helped me realize that it isn’t that being at the bottom of the market is the causal mechanism but that its correlated with a business model that is unattractive to its competitor.

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  16. proslijedio/la je Tweet
    24. sij

    "It's easier to hold your principles 100 percent of the time than it is to hold them 98 percent of the time." -- Clayton Christensen, giant of enterprise, RIP

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  17. proslijedio/la je Tweet
    23. sij
    Odgovor korisnicima

    Nature seems to have limited affinity for people over ~30. All the fasting & cold exposure in the world won’t make a material difference. Only «Youthful signalomic recalibration» via defined pharmacology (hopefully as natural as possible) can help us

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  18. proslijedio/la je Tweet
    5. lip 2019.

    “We stopped a bunch of things on the theory of ‘do less better.’ Next, I believe if you’re going to change you’ve got to have some evidence of success inside your own company." -Scott Cook, Intuit Watch the full video:

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  19. proslijedio/la je Tweet

    Another amazing talk. The future of cancer research unfolding! James P. Allison – Nobel Lecture

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  20. proslijedio/la je Tweet
    22. sij
    Odgovor korisniku/ci

    Likely as always: Abrogation of mitigates obesity-induced oxidative stress, proinflammation, and insulin resistance Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity

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  21. proslijedio/la je Tweet
    22. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    More confirmation from : "the study of levels in the knee joint of human patients suggests that active TGFβ levels are very low or absent in healthy articular joints, while drastically elevate in joint diseases such as "

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