You might wish to chat with the defense or satellite industries--both of which regularly need FPGA tool chains that support our of date FPGAs. Updating an FPGA configuration on a satellite is all the more challenging when the FPGA is already out of date on the launch pad.
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I don't know what of my other stuff, if any, is used in ALS specifically. (Those machines are also being changed constantly.) But in general LBNL is also using Yosys for various tasks and have at least started to evaluate nextpnr for ECP5.
The reason I mentioned PicoRV32 in ALS is because safety interlocks are a pretty permanent part of the system (so I can be pretty sure it's still in there) and interlocks are a critical component, so they definitely trust those open source cores with >$20M on the line.