On most scientific issues, even if I turbo disagree with somebody, I still often continue liking them as a person. Sometimes even more so.
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There have been cases I've received rude emails but often they get followed up by implicit or sometimes even explicit apologies.

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Other times I get ridiculous walls of text which I never as a rule reply to... especially when "sorry" is a tiny little word.
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On the whole, I treasure friends in science even if we really disagree on how to tackle a problem, what the problem even is, etc.
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Also tangent, but I'm aware of people who follow me who pretty much only interact with me by faving tweets which disagree with me. Amusing.
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So I suppose when I come out with a paper /preprint they turbo disagree with, they are unlikely to unfollow since obv already disagree!
End of conversation
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