the more genes you have, the healthier you are. that's how it works right
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Replying to @stellahymmne
unfortunately that's kind of literally true in many cases. XX people are less susceptible to many diseases than XY people are because the extra X provides some protection
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Replying to @bi_gendian
it's true that XY gives you more susceptibility to genetic problems, but unless we're talking about a specific mutation it doesn't seem that bad. I'm not aware of any X-specific mutations that like dormant until later in life, so if you inherited any problems you'd know by now.
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Replying to @stellahymmne
there are unfortunately a bunch... it's called antagonistic pleiotropy and it's a large part of the reason that the average XY lifespan is shorter than the average XX lifespan :/
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Replying to @bi_gendian @stellahymmne
Hmm, not sure that's true? I'm not an expert. But X inactivation means it doesn't matter if one has XY or XX only one X is active. https://en.m.wikipedia.org/wiki/X-inactivation …
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Replying to @o_guest @stellahymmne
I know about X inactivation, but unfortunately having two copies of a gene means you're more likely to have at least one functioning copy. this is what allows XX people to act as carriers for otherwise lethal mutations
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Replying to @o_guest @stellahymmne
it just bothers me because the Y chromosome is clearly doing good stuff but people often equate it with masculinity
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Replying to @bi_gendian @stellahymmne
Reductionists don't understand. Evergreen point.
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Replying to @o_guest @stellahymmne
it's a problem for health bc XY individuals will have declining health as their body starts to reject the Y chromosome upon getting older. cw gendering in thishttps://www.sciencedaily.com/releases/2014/04/140428121205.htm …
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Maybe we in future we can crisper everybody with XX, if there is a health component. (Being a bit facetious!) How do these things play out when they interact with the cultural correlations of karyotypes? Like women (cis and trans) live longer with respect to genetic diseases?
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Replying to @o_guest @stellahymmne
that I don't know. my hunch is that in terms of longevity, assuming you live past 50, the expected lifespan ranking is 1. trans women 2. cis women 3. cis men 4. trans men
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