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  1. 24. velj 2019.

    It was a real pleasure working with Mark on this article.

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  2. 2. velj 2019.

    >1,000 neurons imaged and reconstructed with complete, whole-brain axon arborizations. Great work by Jayaram Chandrashekar and large number of very talented collaborators at Janelia.

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  3. 13. stu 2018.

    Giving a talk at Old Ox Brewery in Ashburn, tonight at 6:30. Come out and enjoy a cold one!

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  4. 9. stu 2018.

    tSNE plot of single-cell RNA-seq data from subiculum kinda looks like a map of the world. What happened to South America and India?

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  5. 9. stu 2018.

    Mark, congratulations on this well-deserved honor!

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  6. 9. stu 2018.
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  7. 2. stu 2018.

    Please check out our latest paper on transcriptional cell types in the subiculum. . Eight types of pyramidal neurons in the subiculum (mouse). Beautiful work from a talented team led by

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  8. 18. lis 2018.

    21/ Thanks for reading my first thread to the end! Over and out.

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  9. 18. lis 2018.

    20/ Illustrations in Figure 6 are by Julia Kuhl:

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  10. 18. lis 2018.

    19/ As usual, we got a lot of help from several people at Janelia and elsewhere; they are all mentioned in the Acknowledgements. Thanks everyone!

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  11. 18. lis 2018.

    18/ The first author is a former postdoc, Tara Deemyad (, now at U. Pitt.). The middle author is Joel Lüthi, a former summer undergrad (, now at U. Zürich).

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  12. 18. lis 2018.

    17/ Once again, here’s a link to our paper: . We hope you enjoy it.

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  13. 18. lis 2018.

    16/ The big open question now is under which conditions barrage firing occurs in vivo without artificial stimulation.

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  14. 18. lis 2018.

    15/ The Bekkers lab has also induced barrage firing in vivo:

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  15. 18. lis 2018.

    14/ Although these experiments were done in hippocampal area CA1, we have also observed barrage firing all over the hippocampus and in the neocortex (unpublished).

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  16. 18. lis 2018.

    13/ Signaling mechanisms are still somewhat mysterious, but the paper describes a number of pharmacological manipulations that lead us to a model, described in the paper and illustrated here.

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  17. 18. lis 2018.

    12/ Loss of function: Buffering calcium in the astrocytic network prevents barrage firing (Figure 4).

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  18. 18. lis 2018.

    11/ Similarly, stimulating astrocytes with light-activation of channelrhodopsin enhances barrage firing (Figure 5).

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  19. 18. lis 2018.

    10/ Gain of function: Promoting the depolarization of astrocytes (chemically) enhances barrage firing (Figure 2).

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  20. 18. lis 2018.

    9/ Correlation: Astroctyes depolarize (Figure 1) and generate calcium signals (Figure 3) in response to stimulation of the NPY interneurons. All this happens prior to the onset of barrage firing.

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