Oh, so we disagree less than I thought!
My preferred regulatory regime would indeed create finer grained distinctions and rely more on individuals and their doctors to make treatment decisions.
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I think that's consistent with the overall regulatory posture. Tens of thousands of vaccinated people will probably die from Delta, but the FDA thinks that those deaths are worth the conservatism on EUAs, I think?
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Almost certainly is, like, a 1 in 1,000 hazard ratio, right? If that's the case, there will definitely be hundreds to thousands of Delta deaths in vaccinated people in the US alone, if my math is right.
And separately, there's a lot of harm that I care about other than death.
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For sure, although I, personally, would want one even after seeing e.g., animal challenge trial data.
The thing I really wish is that we'd started these trials in April when we identified Delta, in which case we'd be done with all of that by now..
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Well, yes, but I expect that they would have done that under a different regulatory (and vaccine purchasing) regime, which is what I would advocate for.
I don't think it's fair to pin this on the companies in this case.
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