Every wet lab I've visited has solved this with a lone desktop computer, long forced off the network by IT, running vanilla Windows XP so it can talk to an instrument purchased by the PI with their startup grant in 2003. Woe betide the student who "upgrades" it.
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Replying to @geoffreylitt @rsnous and @maxkreminski
A one-click process to produce a hardware box which will permanently run a specific piece of software