Noah Simons

@noahdsimons

Postdoc at Duke University :: NIH NRSA Fellow :: Biological anthropologist researching the consequences of stress and aging on single-cell gene regulation

Vrijeme pridruživanja: ožujak 2011.

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  1. Prikvačeni tweet
    23. svi 2019.

    Check out our new paper: Genome-wide patterns of gene expression in a wild primate indicate species-specific mechanisms associated with tolerance to natural simian immunodeficiency virus infection

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  2. proslijedio/la je Tweet
    28. sij

    New lab preprint! Eating a western diet changes behavior and induces a proinflammatory monocyte phenotype (compared to a Mediterranean diet). led this fantastic collaboration with Tom Register and Carol Shively at WFU.

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  3. 25. sij

    Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chrom...

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  4. 24. sij

    Single-cell transcriptional diversity is a hallmark of developmental potential

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  5. 18. sij

    Global problems need social science

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  6. proslijedio/la je Tweet
    17. sij

    Which teams take the best shots? And which have the best shooters? Here are the best shooting teams across both metrics, gleaned from shot location data

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    Each batch-effect removal method has its advantages and limitations. LIGER, Harmony, and Seurat 3 to be the top batch mixing methods today | A benchmark of batch-effect correction methods for single-cell RNA sequencing data | Genome Biology | Full Text

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    A study in identifies specific biological pathways along which individuals age over time, called ageotypes.

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  9. 16. sij

    Genetic analysis of social-class mobility in five longitudinal studies

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  10. proslijedio/la je Tweet
    14. sij

    Count data can be modeled with many different probability distributions and it's sometimes easy to confuse them. I typed up a review of popular distributions such as multinomial and negative binomial showing how they are related mathematically

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  11. 8. sij

    Cellular senescence and chronological age in various human tissues: A systematic review and meta‐analysis

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  12. 8. sij
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  13. proslijedio/la je Tweet
    7. sij

    Nearly 60 years later, the first three paragraphs of Dobzhansky's essay on "Genetics and Equality" continue to be pitch-perfect. (1/n)

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  14. 6. sij

    Congrats to one of my oldest and best friends on finishing her PhD. Well done Dr. Dunayer!!!

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  15. 28. pro 2019.
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  16. proslijedio/la je Tweet
    26. pro 2019.

    The transcriptome dynamics of single cells during the cell cycle

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  17. proslijedio/la je Tweet
    23. pro 2019.

    Interested in statistical models for scRNA-seq? Happy holidays! Two papers in : * GLM-PCA from and : * Our sctransform package (by Christoph Hafemeister) for normalization and variance stabilization:

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    Happy Christmas (eve), everyone!😊Here's our quick traditional reminder of the equation for a merry Christmas! 😉

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  19. proslijedio/la je Tweet
    23. pro 2019.

    Estimating allele-specific expression of SNVs from 10x Genomics Single-Cell RNA-Sequencing Data

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  20. proslijedio/la je Tweet
    20. pro 2019.

    This is so crazy. Take out the queen, and workers ant fight, with the winner *transforming* into a queen, gaining additional lifespan. Using scRNA-seq, authors show these "queens" have more glia, suggesting that that helps increase brain health to enable longer lifespan.

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  21. proslijedio/la je Tweet
    19. pro 2019.
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