I feel repeatedly drawn to this thread on how the evolution of plastic behaviors can come from totally unexpected or unpredictable sourceshttps://twitter.com/neuroecology/status/1184906479628894210 …
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Behavioral flexibility varies between different members of the same species One source of the variation [in C. elegans] is a dendritic scaffold protein that alters neuropeptide expression Obviously [by Beets, de Bono] https://www.cell.com/neuron/fulltext/S0896-6273(19)30849-9?rss=yes …pic.twitter.com/nMRGQvDxo6
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But is it unexpected/unpredictable because we don't know enough about the overall biology? Or because the evolutionary forces are in some sense cloaked from our methods?
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I did a poll once where I asked if people thought that genes required for a trait found using forward screens would be the same genes that vary in populations that underly variability in that trait and about half the people said yes and I still don't get what they were thinking.
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I mean, I'm not super surprised. Phenotypic variation isn't something that we think about, like, at all in most neuroscience
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