Oh absolutely not, A monopoly is hugely inefficient and we only grant them out of reverence to either political pressure or in deference to intellectual property.
Only the people who care will, and they will probably care enough to do so well enough to only poison people as they intend to mostly?
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A tiny minority will spend the $ and run the risk. But ultimately we're talking about a fraction of the population who use these substances anyway.
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That will be lower cost, lower profit, and the risk will be even dumber and unusual of one to take.
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