Key message: case fatality depends on which cases you look at. High in the relatively severe subset reported in Hubei. Lower in (mostly milder)traveller cases, 1% (.25-4) in all infectionshttps://twitter.com/MRC_Outbreak/status/1226765905306234881 …
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Our CFR estimates place 2019-nCoV in the same range as the flu pandemics of the 20th century. Which pandemic (1918, 57 or 68) is currently unclear. And whether the global impact is comparable depends on what proportion of people are eventually infected.
Last, data from China suggest that while all ages can be infected (risk of being a case fairly constant across adult ages), the severity of infection and risk of death increases sharply in the elderly (>70) and those with pre-existing health conditions
Had SARS also 0-24 ! days incubation time?https://www.medrxiv.org/content/10.1101/2020.02.06.20020974v1 …
So nothing much to worry about?
Great work Neil! I think I choose the wrong field
1/2 The one possible (a bit crazy but not implausible) reason why it does not yet spread as well outside of Hubei and Wuhan is the level of chemical air contamination in Wuhan which might have lowered the immunity of the population.
2/2 The residents were protesting against the pollution number of times in the past and there is also some research on it: http://www.nature.com/articles/srep40482 … http://www.cnn.com/2019/07/10/asia/china-wuhan-pollution-problems-intl-hnk/index.html ….
Neil - hoping you can clarify a data point here. SARS CFR in the end was 9.6%. Past flu epidemics significantly lower. You say here that estimates are similar to both - not attempting to disagree, just understand your findings.
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