To be clear, I do not claim credit for this idea! I am adding detail to the tweet from @stephaniemlee. Folks at Fred Hutch are leading the proposal here. I am a supporter!
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To measure vaccine impact on transmission, we can run trials that use contact tracing to monitor spread from vaccinated and unvaccinated participants. College students are ideal since they aren’t prioritized for an EUA, and transmission is higher in congregate settings.https://twitter.com/stephaniemlee/status/1340127045582385152 …
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Did they measure viral loads from vaccinated people?
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Viral load and duration of shedding, but only from symptomatic cases.
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UF STP might be interested in that
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Is this a narrow use case for HCTs? Run daily antigen tests on a small set of young people? You may not even need a placebo arm, and it hardly feels unethical if you’re administering a vaccine with 95% efficacy at reducing symptomatic Covid...
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That seems like it would be very difficult to study. To get asymptomatic spread, you have to have virus replicating in your sinuses. If vaccinated, that wouldn't happen much if at all.
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I have really been wondering how we can achieve herd immunity if the vaccines don’t prevent asymptotic spread? How would the people who don’t get the vaccine be protected if this isn’t the case?
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I really wonder that too. Because if they don’t prevent asymptomatic spread, they’re essentially just a drug that suppresses symptoms. When the effect wears off, we’re right back where we started, but probably in a worse place, with many feeling (& acting) like they’re “immune.”
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"not eligible soon" but we're going to move them up the list before immunocompromised? I know we want answers to these questions, but there are better ways to do it. We could require all the HCWs in phase 1 to get tested every 2 weeks. Exchange for getting vaccinated so early
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well the control group of the pfizer so called "vaccine" had 10 deaths on 20000 people this is 0.05% letality !! flu is more letal !! so all this buzz on mARN type of "vaccine" is just marketing and we will see it over the coming year
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compare the time and the kinetic of death for the same time...
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