Nature Biomedical EngineeringOvjeren akaunt

@natBME

News from the editors of Nature Biomedical Engineering, a journal for researchers, engineers and clinicians interested in human health. Launched in Jan 2017.

London and Berlin
Vrijeme pridruživanja: siječanj 2016.

Medijski sadržaj

  1. A material encapsulating a cytokine, an adjuvant and tumour-associated antigens elicits, in mice, prophylactic immunity to acute myeloid leukaemia, and eradicates the disease when combined with chemotherapy. [Paper]

  2. Carbon-coated FeCo nanoparticles as sensitive magnetic-particle-imaging tracers with photothermal and magnetothermal properties

  3. Rapid optofluidic detection of biomarkers for traumatic brain injury via surface-enhanced Raman spectroscopy

  4. Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs

  5. Monitoring the turnover of cellular metabolites in vivo via the quantification of signal reductions in proton magnetic resonance spectroscopy after the administration of a deuterated substrate. [Paper]

  6. Odgovor korisniku/ci
  7. The therapeutic dose of small interfering RNA can be reduced by endogenously expressing and packaging the RNA into extracellular vesicles through its integration with the backbone of a highly enriched pre-microRNA. [N&V] [Paper]

  8. A deep-learning algorithm trained with retinal images and subject metadata from the UK Biobank predicts blood-haemoglobin levels. [N&V] [Paper]

  9. An injectable biomaterial vaccine encapsulating antigens associated with acute myeloid leukaemia, dendritic-cell-targeting pro-inflammatory cytokines and an adjuvant protects mice from the disease. [N&V] [Paper]

  10. The editing of single DNA bases in the genome is being optimized for higher editing precision and versatility. [Editorial highlighting three papers by and collaborators]

  11. Large quantities of extracellular vesicles produced via cellular nanoporation, and loaded with endogenously transcribed therapeutic mRNAs and targeting peptides, boost therapeutic outcomes in vivo. [N&V] [Paper]

  12. 1H magnetic resonance spectroscopy of 2H-to-1H exchange quantifies the dynamics of cellular metabolism in vivo

  13. On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology [3/3]

  14. Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips [2/3]

  15. Robotic fluidic coupling and interrogation of multiple vascularized organ chips [1/3]

  16. Negatively charged nanoparticles of about 50 nm in size permit the oral delivery of insulin and other peptide drugs by temporally enhancing the permeability of the intestinal wall. [N&V] [Paper]

  17. In a mouse model of tyrosinaemia, a base editor correcting a splice-site mutation in the Fah gene restores the translation of the functional enzyme, promoting the repopulation of the liver with the corrected cells. [N&V] [Paper]

  18. Harnessing the secreted extracellular matrix to engineer tissues [Comment]

  19. The overexpression of the transcription factor c-Jun improves chimeric-antigen-receptor T-cell functionality and enhances the killing of low-antigen-expressing liquid and solid cancers in mice. [N&V on a paper] [Paper]

  20. The editing of single DNA bases in the genome is being optimized for higher editing precision and versatility. [Editorial highlighting three papers by ’s team and collaborators]

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