Nature Biomedical EngineeringOvjeren akaunt

@natBME

News from the editors of Nature Biomedical Engineering, a journal for researchers, engineers and clinicians interested in human health. Launched in Jan 2017.

London and Berlin
Vrijeme pridruživanja: siječanj 2016.

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    Personalized computational modelling of optimal ablation targets on heart tissue guides the treatment of patients with persistent atrial fibrillation. [N&V] [Paper]

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    Computationally designed antibody–drug conjugates easily self-assemble via affinity ligands that non-covalently link a therapeutic drug to conserved sites on native IgG antibodies. [N&V] [ Paper]

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    Leukocyte function assessed via serial microlitre sampling of peripheral blood from sepsis patients correlates with disease severity

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    The computational design of self-assembling antibody–drug conjugates via affinity ligands yields homogenous and stable conjugates that form in less than 8 minutes. [Paper]

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    Opportunities and challenges of translational 3D bioprinting [Perspective]

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    Anionic nanoparticles increase intestinal permeability and enable the oral delivery of proteins, as shown with the delivery of insulin in healthy, hyperglycaemic, and diabetic mice. [Paper]

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    Growth factors with enhanced syndecan binding generate tonic signalling and promote tissue healing

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  9. Linking ten organs-on-chips to predict how a human body metabolizes drugs.

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    Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability

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    Computationally designed antibody–drug conjugates self-assembled via affinity ligands

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  12. The therapeutic dose of small interfering RNA can be reduced by endogenously expressing and packaging the RNA into extracellular vesicles through its integration with the backbone of a highly enriched pre-microRNA. [N&V] [Paper]

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  13. A deep-learning algorithm trained with retinal images and subject metadata from the UK Biobank predicts blood-haemoglobin levels. [N&V] [Paper]

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    30. sij

    Join us at with , & ! Register by Feb 29 for early bird pricing, and submit your abstracts by April 30 here:

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  15. An injectable biomaterial vaccine encapsulating antigens associated with acute myeloid leukaemia, dendritic-cell-targeting pro-inflammatory cytokines and an adjuvant protects mice from the disease. [N&V] [Paper]

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  16. The editing of single DNA bases in the genome is being optimized for higher editing precision and versatility. [Editorial highlighting three papers by and collaborators]

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  17. Large quantities of extracellular vesicles produced via cellular nanoporation, and loaded with endogenously transcribed therapeutic mRNAs and targeting peptides, boost therapeutic outcomes in vivo. [N&V] [Paper]

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    27. sij
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  19. 1H magnetic resonance spectroscopy of 2H-to-1H exchange quantifies the dynamics of cellular metabolism in vivo

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  20. On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology [3/3]

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  21. Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips [2/3]

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