A *very* important point: at this point, the gov't could save billions of $$ (not to mention lives) by sequencing the genome of everyone in the UK, identifying groups at high risk from cancer, and investing in regular screening/detection and early prevention for that group.
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e.g. Assume, for breast cancer: -- 32m population (i.e. women) -- Sequencing cost = $100 -- Savings from early treatment = $20k per person -- High risk-population = top 10% (i.e. 3.2m), of which 33% (~1m) will get breast cancer --> B = $20k * 1m = $20bn; C = $100 * 32m = $3.2bn
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The benefit way outweighs the cost! See https://res.mdpi.com/data/data-02-00030/article_deploy/data-02-00030-v2.pdf … … … for a justification of the savings (note that 20k is conservative, so actually the benefit is higher). Suspect the NHS will head in this direction soon, which is *amazing*.
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