Turns out some polymeric biomaterials can stimulate the immune system and help vaccines do their jobs (they act as adjuvants). Inspired by this, they made biomaterials exclusively from immunostimulatory molecules, with no extra carrier material.pic.twitter.com/UC0q5lqG1m
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By carrying the adjuvants (different TLR agonists) they can change the immune signalling response to the material.pic.twitter.com/WPtQ0gQZuU
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On the other side of the coin, an overactive immune system can lead to autoimmune disease (MS, rheumatoid arthritis, etc.) Controlling TLR signalling could be a way to train immune cells not to attack self.pic.twitter.com/4cPWVR2QYE
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The lymph nodes are like the training centers for the immune system. By engineering the lymph node environment, they can modify how T cells are trained, pushing toward regulatory functions vs. attack.pic.twitter.com/vK5vzMe8qy
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