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Prikvačeni tweet
Here’s a link to read and download for those without a subscription. Check it out! https://authors.elsevier.com/c/1a8FUL7PXYX0a https://twitter.com/ScacheriLab/status/1197542531061317632 …
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Andrew Morton proslijedio/la je Tweet
Don't Panic! If you have ATAC-seq data and you're not sure of the best way to analyze it
@alexyfyf,@methylnick and co have written a review to help you. You'll soon know where your towel is. https://genomebiology.biomedcentral.com/articles/10.1186/s13059-020-1929-3 …pic.twitter.com/GfiEg0VbWh
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Andrew Morton proslijedio/la je Tweet
I love Super Bowl statistics. (“No team that has failed to convert at least 35% of their 3rd downs has gone on to win” etc.) They are the best introduction to p-hacking that can be found outside major journals.
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Andrew Morton proslijedio/la je Tweet
Excited to announce the latest extension of CoGAPS for scATAC-seq led by the great Rossin Erbe! Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets | bioRxivhttps://www.biorxiv.org/content/10.1101/2020.01.30.927129v1 …
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Andrew Morton proslijedio/la je Tweet
Brain cancer cells hijack genetic “on switches” to drive the growth of tumors: https://www.cancer.gov/news-events/cancer-currents-blog/2020/glioblastoma-egfr-dna-circles …
#braintumor#glioblastoma#btsmpic.twitter.com/YJ8Zv4IyPR
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Andrew Morton proslijedio/la je Tweet
We wrote the review that I wished I'd had when I started my PhD in gene regulation & genomics! Read for our take on the past 40 yrs of enhancer biology, a def of an "enhancer", and how we think modern tech (like CRISPR screens) will enable the next era of understanding the genomehttps://twitter.com/NatureRevGenet/status/1222103381306675200 …
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Andrew Morton proslijedio/la je Tweet
Inspired by
@RoxanaDaneshjou recent tweet on the "80/20" challenge of the physician scientist (https://twitter.com/RoxanaDaneshjou/status/1221201794300121088 …) my two cents. Worklife balance to be discussed another time@tmprowell...Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Andrew Morton proslijedio/la je Tweet
Our preprint on AmpliconReconstructor, which reconstructs complex amplifications in cancer - leveraging
@bionanogenomics optical mapping and WGS data is out now! We show megabase-scale reconstructions of circular#ecDNA, a 10+ Mbp breakage fusion bridge, and more.https://twitter.com/biorxiv_bioinfo/status/1220470387177402372 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Andrew Morton proslijedio/la je Tweet
Our collaborative work with the Pasca lab mapping the chromatin accessibilty dynamics of human forebrain development just came out! Congrats to Alex, Nasa, and Jimena!https://science.sciencemag.org/content/367/6476/eaay1645 …
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Andrew Morton proslijedio/la je Tweet
My team's latest publication deepening our understanding of the noncoding cancer genome: Noncoding mutations target cis -regulatory elements of the FOXA1 plexus in prostate cancerhttp://disq.us/t/3lj6ta2
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Andrew Morton proslijedio/la je Tweet
I am very excited to share our latest work on candidate non-coding cancer driver mutations published in
@MolecularCell /w@Hz_is_frequency@LiisUuskula@Karin8787@wilson_md et al#PCAWG@OICR_news https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30957-8 … Thread: /17Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Andrew Morton proslijedio/la je Tweet
Another beauty on mechanisms of focal genomic instability from the Pellman lab:https://www.biorxiv.org/content/10.1101/835058v1 …
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Andrew Morton proslijedio/la je Tweet
The prospective clinical MSKCC NGS cohort is now >50,000 samples sequenced. Thanks to the hundreds of physicians, laboratory technicians, data scientists, nurses and support staff
@sloan_kettering who have made this initiative possible. A few thoughts on what we have learned.pic.twitter.com/9ra4tuqUg7
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Andrew Morton proslijedio/la je Tweet
Our latest using single-cell ATAC-seq and HiChIP to identify putative functional risk loci in Alzheimer’s and Parkinson’s disease. This was an amazing collaboration between
@HowardYChang@anshulkundaje@sbmontgom and the twitterless Tom Montine. https://www.biorxiv.org/content/10.1101/2020.01.06.896159v1 … 1/nPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Andrew Morton proslijedio/la je Tweet
Preprint alert! We are excited to share our latest work that uncovers key differences in the gene regulatory landscape between naïve and primed human pluripotent stem cells. 1/5https://www.biorxiv.org/content/10.1101/2019.12.13.875286v1 …
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Andrew Morton proslijedio/la je Tweet
Check out our paper, online today
@NatureGenet ! With Richard Koche@sloan_kettering ,@eliasrfos from the Torrents lab@BSC_CNS and colleagues@ChariteBerlin@MDC_Berlin, we describe that circular DNA serves as a substrate for oncogenic genome remodelling https://go.nature.com/2YTyckR pic.twitter.com/KddAUO6vlB
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Andrew Morton proslijedio/la je Tweet
Stochastic dynamics of extra-chromosomal DNA. Work with
@huang_weini and@ab_in_ on a fascinating aspect of cancer evolution. Shortest summary: The evolutionary dynamics differs a lot compared to classic somatic evolution of SNVs.https://www.biorxiv.org/content/10.1101/2019.12.15.876714v1 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Andrew Morton proslijedio/la je Tweet
My favorite papers challenge biomedical dogma. Here's my summary of the ones in 2019 that provided evidentiary shakeups (2nd annual list) [let me know the ones I missed]pic.twitter.com/AmBmXZq5ug
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Andrew Morton proslijedio/la je Tweet
1/7 In this new preprint we investigated how CTCF controls genome folding. TLDR: it’s about the CTCF N-terminus. https://biorxiv.org/cgi/content/short/2019.12.13.876177v1 … Collaborative work between lab of
@benoitbruneau,@LCaccianini (Maxime Dahan lab),@gfudenberg (Katherine Pollard lab)Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Andrew Morton proslijedio/la je Tweet
Very excited that our paper on the embryonic origins of childhood kidney cancer is out! Read all about it here:https://science.sciencemag.org/content/366/6470/1247 …
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