Some puzzles: 1) The sex bias in mutations (~3:1 paternal) is close to what is seen in humans, despite differences in spermatogenesis. A similar bias is seen across mammals that reproduce months, years or decades after birth.
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We recently reported that within humans, the sex bias in mutations is stable with parental ages: https://www.pnas.org/content/116/19/9491.short … Both results imply that spermatogenesis is not driving the male bias in mutation. What is?
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A second puzzle: Scally & Durbin (2012) pointed out that the current human mutation rate implies divergence times too old to be consistent with the current understanding of the primate fossil record. Our results suggest the same for baboons. Two simultaneous slowdowns?
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@moorjani_priya, Jeff Wall, Carole Ober and Alva StrandPrikaži ovu nit
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