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misen__'s profile
Mi'sen
Mi'sen
Mi'sen
@misen__

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Mi'sen

@misen__

I like to sit on my arse and relax. Genially mad. Romancing neurotypicals.

Sphere of Enjoyment
Joined October 2017

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    1.  🐜 💩 🐻 💛‏ @ultimape 14 Apr 2019
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      Neat, a clinical trial on the topic of Minocycline + Alzheimer's. (https://clinicaltrials.gov/ct2/show/results/NCT01463384 …) Recent paper reviewing options for Amyloidoses http://doi.org/10.1021/acschemneuro.8b00402 … a previous review of Caspase inhibitors https://doi.org/10.1080/13543776.2017.1378426 … and initial idea:http://doi.org/10.1021/jm400161p …

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    2.  🐜 💩 🐻 💛‏ @ultimape 14 Apr 2019
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      Because of course rosacea is a risk factor for type 2 diabetes. https://doi.org/10.1684/ejd.2016.2748 …

      1 reply 0 retweets 1 like
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    3.  🐜 💩 🐻 💛‏ @ultimape 14 Apr 2019
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      What if the relationship between Alzhimer's and Type 2 Diabetes is because they are both down stream of a similar biological cause?https://doi.org/10.1093/epirev/mxs012 …

      1 reply 0 retweets 0 likes
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    4.  🐜 💩 🐻 💛‏ @ultimape 14 Apr 2019
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       🐜 💩 🐻 💛 Retweeted  🐜 💩 🐻 💛

      I've had this idea before, but thru a different path of reasoning. Now it seems I've accidentally discovered a couple of antibacterials that might help with resetting a gut microbiome.https://twitter.com/ultimape/status/967700226483081216 …

       🐜 💩 🐻 💛 added,

       🐜 💩 🐻 💛 @ultimape
      Alzhiemer's and Parkinson's Disease both manifest with a clinically notable Sweet-Tooth, and Both exercise and Fasting seem to help. This unintuitive reason why will shock you! Hint: https://lmddgtfy.net/?q=Neuropharmacology%20Journal%20Diabetes%20Type%20II%20medication%20helps%20Alzheimer's%20Disease …
      1 reply 0 retweets 0 likes
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    5.  🐜 💩 🐻 💛‏ @ultimape 14 Apr 2019
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       🐜 💩 🐻 💛 Retweeted  🐜 💩 🐻 💛

      The sweet tooth thing shows up a lot when there is a microbial issue. I've recently concluded that is why we see it among Parkinson'shttps://twitter.com/ultimape/status/1111911609570594816 …

       🐜 💩 🐻 💛 added,

       🐜 💩 🐻 💛 @ultimape
      Replying to @ultimape
      My current suspicion is that Parkinsons isn't caused by microbes/bacteria/virus/fungal invaders, but shows all the symptoms of having a disrupted microbiome ecosystem, hence showing up with skin smells acting as a possible early diagnostic. https://twitter.com/ultimape/status/936437839708983296 …
      1 reply 0 retweets 0 likes
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    6.  🐜 💩 🐻 💛‏ @ultimape 14 Apr 2019
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       🐜 💩 🐻 💛 Retweeted  🐜 💩 🐻 💛

      There's also a lot to be said about how CO2 levels seem to change cortisol signaling via action on the amygdala. I think that might be why see SIBO and Yeast issues crop up as rumor'd causal issues. Perhaps it's just amplifying existing underlying issues?https://twitter.com/ultimape/status/1115272951195213825 …

       🐜 💩 🐻 💛 added,

       🐜 💩 🐻 💛 @ultimape
      I don't think *all* autism symptoms are caused by yeast overgrowth. But my suspicion about autism in general is it's an immune system regulation issue impacting mitochonrial function - hence why we see high levels of dysbiosis. The candidia and SIBO seems more like a symptom.
      Show this thread
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    7.  🐜 💩 🐻 💛‏ @ultimape 14 Apr 2019
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      Cortisol levels are a risk factor for Alzhiemr's, and there was a study on how cortisol may be inherited.https://doi.org/10.1023/A:1025321609994 …

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    8.  🐜 💩 🐻 💛‏ @ultimape 14 Apr 2019
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      Cortisol regulation is weird in autism, schizophrenia, and diabetes type 2/pcos. I think a portion of 'inherited' is via vertical microbiome transfer; is perhaps what the genetic inheritance is giving a proclivity for. Microbiome signaling via cortisol:http://dx.doi.org/10.1080/19490976.2017.1353849 …

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    9.  🐜 💩 🐻 💛‏ @ultimape 14 Apr 2019
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      This whole thread is really about trying to figure out why CBD oil seems to reduce my stress & help me sleep. TL;DR: I may have figured out a way to fix my sleep issues medicinally. The only other thing is red wine. Following in @tferriss's footsteps.https://invidio.us/watch?v=cmHFa0W89II …

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    10.  🐜 💩 🐻 💛‏ @ultimape 14 Apr 2019
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       🐜 💩 🐻 💛 Retweeted  🐜 💩 🐻 💛

      I can't find any direct links between CBD oil and cortisol reduction. So I've been exploring other ways it might be impacting my sleep issue. I suspect I have an imbalance in how my body maintains some neruochemicals.https://twitter.com/ultimape/status/667904410887036928 …

       🐜 💩 🐻 💛 added,

       🐜 💩 🐻 💛 @ultimape
      Replying to @ultimape
      "... higher peak cortisol levels and prolonged duration and recovery of cortisol elevation [...] with autism." http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245359/ …
      2 replies 0 retweets 0 likes
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      Mi'sen‏ @misen__ 16 Aug 2019
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      Replying to @ultimape

      Do you have any recommendations re: CBD dosing? I've been avoiding that hype train because quality control is terrible in the UK, but you are making me want to try it.

      8:39 AM - 16 Aug 2019
      1 reply 0 retweets 0 likes
        1. New conversation
        1.  🐜 💩 🐻 💛‏ @ultimape 16 Aug 2019
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          Replying to @misen__

          Seems to vary based on the condition. I can't speak for dosing because I'm not really a doctor. Oddly its easier to find research on dogs and arthritis and anxiety reduction than anything else more complex. There's good literature on epilepsy out there.

          1 reply 0 retweets 1 like
        2.  🐜 💩 🐻 💛‏ @ultimape 16 Aug 2019
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          Replying to @ultimape @misen__

          I don't think my dosing recomendation would be a good way to go. Too much triggers anxiety in me. I think it overwhelms serotonin production and triggers intestinal problems for the same reason there's a suspicion it may help with IBS and menstrual pain.

          1 reply 0 retweets 0 likes
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