The NIH's "high risk" grant programs: https://commonfund.nih.gov/highrisk Anyone know on what basis they call it high risk? Do they actually track failure rates? Or is it just signalling?
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An idea I like: in a genuine high-risk program, the funder should commit to an independent assessment process (say) three years after grants are given. If at least 50% of grants aren't assessed to have failed, then major changes are to be made.
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That should, in principle, include firing the PO. (Obviously, not something I desire - but if the program is badly off the rails by not taking enough risk, it's legitimate.) Basically, the funder needs skin in the game to convince scientists they're serious about risk.
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Lots of other things needed to make this work - especially to credibly argue to scientists that it's worth their time - but I think something like it could work.
End of conversation
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