@michael_nielsen however, strain variation and polymorphism complicate matters, along with so-called "pan genomes".
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Replying to @ctitusbrown
@michael_nielsen I personally think a good operational definition is "do sequences from these two organisms assemble together" :)1 reply 0 retweets 2 likes -
Replying to @ctitusbrown
@michael_nielsen sort of a computational definition of sex. But I've never explored the idea.3 replies 0 retweets 2 likes -
Replying to @ctitusbrown
@michael_nielsen if you write something on it, I'm happy to publicize it and join in with everyone in telling you why it's wrong. :)2 replies 0 retweets 2 likes -
Replying to @ctitusbrown
@ctitusbrown on known solutions, then use the model to (quickly!) do future "simulations". Apparently useful for doing real time 3d graphics1 reply 0 retweets 1 like -
Replying to @michael_nielsen
@michael_nielsen you're assuming we have a good objective function. I'm not sure we do :)2 replies 0 retweets 1 like -
Replying to @ctitusbrown
@ctitusbrown So with my genome and a hippo genome the model would be trained to say "not the same species"1 reply 0 retweets 0 likes -
Replying to @michael_nielsen
@michael_nielsen sure, but in addition to epistemological confusion, I would worry about sampling bias in training set.2 replies 0 retweets 0 likes -
Replying to @ctitusbrown
@michael_nielsen also not entirely sure that the way we think about species is interesting. corner cases <=> sampling bias rel'n.1 reply 0 retweets 1 like -
Replying to @ctitusbrown
@michael_nielsen anyways, off to do some stuff with my two kids. laters!1 reply 0 retweets 1 like
@ctitusbrown Have fun! Thanks for the convo!
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Replying to @michael_nielsen
@michael_nielsen the ANI paper is a good read. Nice, straightforward, simple, not terribly wrong :)0 replies 0 retweets 1 likeThanks. Twitter will use this to make your timeline better. UndoUndo
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