Is there a good algorithm for determining whether two genomes come from the same or different species? (G Scholar doesn't imm show a'thing)
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Replying to @ctitusbrown
@michael_nielsen well, ok, not really. It boils down to def'n of species. In bacteria, see Kostas work: http://www.ncbi.nlm.nih.gov/pubmed/261504202 replies 2 retweets 3 likes -
Replying to @ctitusbrown
@michael_nielsen however, strain variation and polymorphism complicate matters, along with so-called "pan genomes".1 reply 0 retweets 1 like -
Replying to @ctitusbrown
@michael_nielsen I personally think a good operational definition is "do sequences from these two organisms assemble together" :)1 reply 0 retweets 2 likes -
Replying to @ctitusbrown
@michael_nielsen sort of a computational definition of sex. But I've never explored the idea.3 replies 0 retweets 2 likes -
Replying to @ctitusbrown
@michael_nielsen if you write something on it, I'm happy to publicize it and join in with everyone in telling you why it's wrong. :)2 replies 0 retweets 2 likes -
Replying to @ctitusbrown
@ctitusbrown I'm just curious at this point. A related fun problem would be to train a classifier to solve the problem.3 replies 0 retweets 0 likes
@ctitusbrown This kind of idea has been used to simulate fluids. Navier-Stokes equations hard to simulate. So train a regression model
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