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michael_nielsen's profile
michael_nielsen
michael_nielsen
michael_nielsen
@michael_nielsen

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michael_nielsen

@michael_nielsen

Searching for the numinous. Co-purveyor of https://quantum.country/ 

San Francisco, CA
michaelnielsen.org
Joined July 2008

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    1. Erik Torenberg‏Verified account @eriktorenberg Jun 27
      • Report Tweet

      Erik Torenberg Retweeted Erik Torenberg

      Biology Twitter, same questions: What's the state of biology today? What's the biggest contribution the field of biology has made in the last 50 years? What's the biggest contribution you predict it makes in the next 50?https://twitter.com/eriktorenberg/status/1143901794977796096 …

      Erik Torenberg added,

      Erik TorenbergVerified account @eriktorenberg
      Philosophy Twitter: What's the state of academic philosophy today? What's the biggest contribution the field of philosophy has made in the last 50-100 years? What's the biggest question to answer in the next 50?
      6 replies 1 retweet 33 likes
    2. michael_nielsen‏ @michael_nielsen Jun 27
      • Report Tweet
      Replying to @eriktorenberg

      From the vantage point of a thousand years from now? Archaea, Sanger's work on sequencing (& all it precipitated, eg PCR, shotgun sequencing etc), and CRISPR all seem like plausible candidates.

      3 replies 0 retweets 11 likes
    3. Kevin Simler‏ @KevinSimler Jun 27
      • Report Tweet
      Replying to @michael_nielsen @eriktorenberg

      Can you say more about why archaea is a big deal?

      2 replies 0 retweets 2 likes
    4. michael_nielsen‏ @michael_nielsen Jun 27
      • Report Tweet
      Replying to @KevinSimler @eriktorenberg

      Discovery of a third major type of life (apart from bacteria and eukaryotes). It's just immense. Incidentally, iap, the gene that led to CRISPR, seems to be present in most archaea, and I believe that's one of the things that led to early interest in it

      2 replies 0 retweets 7 likes
    5. michael_nielsen‏ @michael_nielsen Jun 27
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      Replying to @michael_nielsen @KevinSimler @eriktorenberg

      (Though it was first identified in bacteria. IIRC, it's believed to be present in most archaea, and helps function as a kind of immune system for them. Again: not a biologist!)

      1 reply 0 retweets 2 likes
    6. Kevin Simler‏ @KevinSimler Jun 27
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      Replying to @michael_nielsen @eriktorenberg

      Huh... I was under the impression that they were “basically just bacteria” and therefore not all that interesting. What a n00b!

      1 reply 0 retweets 1 like
    7. michael_nielsen‏ @michael_nielsen Jun 27
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      Replying to @KevinSimler @eriktorenberg

      I don't understand at all deeply why they're so interesting, apart from the obvious - if you have something that split far enough back from bacteria, well, you'd expect to discover a _lot_ of new fundamental processes, and that seems to be the case.

      1 reply 0 retweets 1 like
    8. michael_nielsen‏ @michael_nielsen Jun 27
      • Report Tweet
      Replying to @michael_nielsen @KevinSimler @eriktorenberg

      The biologists who first explained archaea to me - not their field - went into sort of gibbering joy when they realized I didn't know. You could see they just thought this was the most incredible thing, and fell all over themselves explaining awesome archaea-related facts.

      1 reply 0 retweets 6 likes
      michael_nielsen‏ @michael_nielsen Jun 27
      • Report Tweet
      Replying to @michael_nielsen @KevinSimler @eriktorenberg

      (That was a fun conversation. I've rarely seen two more excited, burbling scientists.)

      9:58 PM - 27 Jun 2019
      • 2 Likes
      • zooko Erik Torenberg
      0 replies 0 retweets 2 likes

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